ID   A0A1Y2DRX3_9PEZI        Unreviewed;       679 AA.
AC   A0A1Y2DRX3;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Biotin-protein ligase {ECO:0000313|EMBL:ORY61435.1};
GN   ORFNames=BCR38DRAFT_411308 {ECO:0000313|EMBL:ORY61435.1};
OS   Pseudomassariella vexata.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Pseudomassariaceae; Pseudomassariella.
OX   NCBI_TaxID=1141098 {ECO:0000313|EMBL:ORY61435.1, ECO:0000313|Proteomes:UP000193689};
RN   [1] {ECO:0000313|EMBL:ORY61435.1, ECO:0000313|Proteomes:UP000193689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 129021 {ECO:0000313|EMBL:ORY61435.1,
RC   ECO:0000313|Proteomes:UP000193689};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the biotin--protein ligase family.
CC       {ECO:0000256|ARBA:ARBA00009934}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY61435.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MCFJ01000010; ORY61435.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2DRX3; -.
DR   STRING; 1141098.A0A1Y2DRX3; -.
DR   InParanoid; A0A1Y2DRX3; -.
DR   OrthoDB; 317678at2759; -.
DR   Proteomes; UP000193689; Unassembled WGS sequence.
DR   GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:InterPro.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   CDD; cd16442; BPL; 1.
DR   CDD; cd03144; GATase1_ScBLP_like; 1.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR019197; Biotin-prot_ligase_N.
DR   InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR   InterPro; IPR004143; BPL_LPL_catalytic.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   NCBIfam; TIGR00121; birA_ligase; 1.
DR   PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR   PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR   Pfam; PF03099; BPL_LplA_LipB; 1.
DR   Pfam; PF09825; BPL_N; 1.
DR   SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ORY61435.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193689}.
FT   DOMAIN          396..598
FT                   /note="BPL/LPL catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51733"
FT   REGION          334..357
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        337..351
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   679 AA;  74325 MW;  A3C0AF04407F6ED9 CRC64;
     MAPRKLNVLV YTGAGSTVES VKHAVYSLRR LLSPNYAVIP ITDTVLLKEP WAPTCALLVF
     PGGADLGYCR VLNGAGNILI SQYVRRGGAY LGFCAGGYYG STKCEFEVGN KPMEVVGSRE
     LAFFPGTCRG AAFQGFQYQS EKGARAVKLI VKKDAFKSAG VVPDEVTSYY NGGGVFVPFG
     DARDYEVLAS YASPPNVDGG DENPALVMCK VGMGSALLTG PHPEFSPANL EQHCDIPGYD
     DLIASLRATD EARTNFFKAC LGKLGLDVNQ ETSSVPSLSR LHLSSLGNGD VDDLLHSWEE
     IITRENGEEF IKGENDTFHL EKRETRWGVV DLKESLPSDK TSAQPPTEQG LGASPGSGIV
     DYNTVTKRMV IHDSSWPGTQ ETPYFNHHAF YGNLKAYRDI DTEAEEWGDF LLYGEVVTST
     NTLLDKNHNL LSKAPSGFTL TATTQIAGRG RGSNVWVSPA GSLVFSTVIN HPAHLAPSRP
     IVFIQYISAI AIVEAIKTYD KGYTELPVKL KWPNDIYAVD PSKPASPPTY VKIGGILSNC
     AYSSGSYQIV LGIGLNTTNG RPTTSLDALL PSHLPPFRIE KLLARILTRI EVLYKQFLRQ
     GFSKELEELY YSYWLHGRQI VTLEAHGGVK ARIMGITTDW GLLKAEELGS DDRPTGKMWA
     LQSDENSFDF FRNLVKRKL
//