ID   A0A1Y2DU77_9BASI        Unreviewed;       842 AA.
AC   A0A1Y2DU77;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Histone deacetylase clr3 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BCR35DRAFT_283352 {ECO:0000313|EMBL:ORY62719.1};
OS   Leucosporidium creatinivorum.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Microbotryomycetes; Leucosporidiales; Leucosporidium.
OX   NCBI_TaxID=106004 {ECO:0000313|EMBL:ORY62719.1, ECO:0000313|Proteomes:UP000193467};
RN   [1] {ECO:0000313|EMBL:ORY62719.1, ECO:0000313|Proteomes:UP000193467}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=62-1032 {ECO:0000313|EMBL:ORY62719.1,
RC   ECO:0000313|Proteomes:UP000193467};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY62719.1}.
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DR   EMBL; MCGR01000070; ORY62719.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2DU77; -.
DR   STRING; 106004.A0A1Y2DU77; -.
DR   InParanoid; A0A1Y2DU77; -.
DR   OrthoDB; 124800at2759; -.
DR   Proteomes; UP000193467; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR019154; Arb2-like_domain.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   Pfam; PF09757; Arb2; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193467}.
FT   DOMAIN          191..502
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
FT   DOMAIN          558..785
FT                   /note="Arb2-like"
FT                   /evidence="ECO:0000259|Pfam:PF09757"
FT   REGION          1..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          816..842
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..41
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   842 AA;  92154 MW;  2F6B4387DD596407 CRC64;
     MEQSTQPFTQ AIEQSSLPLL SNSDQPLPPI ASSSTLAADP SQTAAPPVPA APETSQAESQ
     PAVVLSGFAA AQSLAAAKPN PVPYIEPPPY VAPALTSTAA TGPSTGVAAL SHPKQFLTNE
     EREKMTPDQL RETSKSRGVP VAELLSEDEV QKFDTATLRR MGLGRTPSGY CFSSRMTLHK
     QLDSASKDDP HPEQPTRITG IFNRLSLAGL TDRMERIAVR EVVRDEVMLV HSEGHWDRVR
     ATGYQTVDYL ASCSEYFDRL SLYVNPETSR CARLSCGGVI EMCRAVAEGQ IRNGFAIVRP
     PGHHAEPEDA MGFCFFNNVA VAAKWLRTIY DGQQEGASGQ KVKKMDKILI LDWDVHHGNG
     TQKAFWDDPN VLYISIHRHG DGFYPGGNYG AAEMVGEGAG VGFSVNVPFT ETGMGDADYI
     YAFQQVIMPI AYEFAPDIVL VSAGYDAAEG DKLGQFKVSP EGFAHMTHML SVLANGKLVL
     ALEGGYNVDS IVKSAHACVE VLVGDEPRHL QLGPASASAT TAVQEVIKIQ AKHWKCMGFA
     MEPAEELKSA GKVVPVAEML KAHRVYELYH EYELFNVEIS KPELEEAYKD QLLCSPNIYD
     AETLLIFMHD IGSIKSSHTA ATMDVDLERT LLLDTSREVL DWAMKDNKWG VIDVNFLAHL
     PSIKGQVPDR ARDVKLEKEF ATFIWDHIAR LSSAQNIVLF ASGAGCSAMM EIVSKRPDTR
     ERVRACISVL GLEAPPELDA ASGMRSWYKE RSLVMLPSTH VLHDDARKAG KHQKKYGNVY
     RATAEDEGRP IHLLRASLPR IRQFVDERLP APRMMEVDES AAGPAPPKGD GDVEMKSGDI
     VV
//