ID A0A1Y2DWN1_9FUNG Unreviewed; 839 AA.
AC A0A1Y2DWN1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=LY90DRAFT_668266 {ECO:0000313|EMBL:ORY63609.1};
OS Neocallimastix californiae.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Neocallimastigomycetes; Neocallimastigales;
OC Neocallimastigaceae; Neocallimastix.
OX NCBI_TaxID=1754190 {ECO:0000313|EMBL:ORY63609.1, ECO:0000313|Proteomes:UP000193920};
RN [1] {ECO:0000313|EMBL:ORY63609.1, ECO:0000313|Proteomes:UP000193920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G1 {ECO:0000313|EMBL:ORY63609.1,
RC ECO:0000313|Proteomes:UP000193920};
RG DOE Joint Genome Institute;
RA Haitjema C.H., Gilmore S.P., Henske J.K., Solomon K.V., De Groot R.,
RA Kuo A., Mondo S.J., Salamov A.A., Labutti K., Zhao Z., Chiniquy J.,
RA Barry K., Brewer H.M., Purvine S.O., Wright A.T., Boxma B., Van Alen T.,
RA Hackstein J.H., Baker S.E., Grigoriev I.V., O'Malley M.A.;
RT "A Parts List for Fungal Cellulosomes Revealed by Comparative Genomics.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
CC -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC {ECO:0000256|ARBA:ARBA00004987}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY63609.1}.
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DR EMBL; MCOG01000056; ORY63609.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2DWN1; -.
DR STRING; 1754190.A0A1Y2DWN1; -.
DR OrthoDB; 5486783at2759; -.
DR Proteomes; UP000193920; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR42715:SF10; BETA-GLUCOSIDASE F-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023001};
KW Cellulose degradation {ECO:0000256|ARBA:ARBA00023001};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:ORY63609.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023001};
KW Reference proteome {ECO:0000313|Proteomes:UP000193920};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..839
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010999211"
FT DOMAIN 353..424
FT /note="Fibronectin type III-like"
FT /evidence="ECO:0000259|SMART:SM01217"
SQ SEQUENCE 839 AA; 93395 MW; 51D215C2BA7B8F70 CRC64;
MKFFNLIVFS LLFYNLILAS PIKKKCYAKN KKNAAENSEN SEVSEKMNQY EIDHINTLDS
YLSECTILLR KNGDFPIGKS TKQVYLYGNG VRKTIKGGTG SGDVYSRSFD TIEQAFTKAG
FEILSKDYLD EYDKIYTKAK DEFRKKVQSE VTDPMSLMGV IMPEPDYDIP YAKEGDLAIY
VLARISGEGS DRQAVKGDVY LTETERKMIL DLAKGFKKFM LVLNTGGAVD LSGIDEVENI
LLLSQLGVNT SKTLVDIITG DKYPSGKLTT TWTKYEDYPS NDNFGDNDDT DYKEGIYVGY
RYFDTENIDV MYPFGFGLGY TDFEFDVKSA KLSGEKFEVK ASVTNVGKYK GKEVLEVYLS
KPGTTIDEPY QILVGFAKSK ELSPKKKDDL KINFKLSDFA SYDAKTATYF LDEGEYVVRI
GNSSRNTVPC GVIKVDKRIN VKKVENKMGK PEFEDYVPEG KRKQEDLSGV KVFKLKASSI
KEKVVKYNDK YEISEGVKAL SNEEKAKLVI GAFQDGPASV IGSASITAAG AAGETAKVAD
LKPVIMADGP AGLRLAKDYF IDEYGAHSTS GSMAESMVEF VPDEIKAMLI SKPEIPEGTE
ILHQYTTAIP IGTAIAQSWN RKFAELCGDI VGSEMELFKV QLWLAPALNI HRSILCGRNF
EYYSEDPLIS GAFAASITKG VQKHNNTFVT IKHYAANNQE TNRYLNSSNV SERALREIYL
KGFEIAVRES QPKAVMTSYN LINGVHTSES KELTNDILRN EFGFEGIVMT DWVVGLGGNH
KYSGPTPYNV IKATGDIYMP GSKADYEAVL KALKEGTLSI EELEMSASRI YNLSKEIFN
//
