ID A0A1Y2E091_9PEZI Unreviewed; 507 AA.
AC A0A1Y2E091;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Flavonoid 3',5'-hydroxylase {ECO:0000313|EMBL:ORY64953.1};
GN ORFNames=BCR38DRAFT_457236 {ECO:0000313|EMBL:ORY64953.1};
OS Pseudomassariella vexata.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Pseudomassariaceae; Pseudomassariella.
OX NCBI_TaxID=1141098 {ECO:0000313|EMBL:ORY64953.1, ECO:0000313|Proteomes:UP000193689};
RN [1] {ECO:0000313|EMBL:ORY64953.1, ECO:0000313|Proteomes:UP000193689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 129021 {ECO:0000313|EMBL:ORY64953.1,
RC ECO:0000313|Proteomes:UP000193689};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY64953.1}.
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DR EMBL; MCFJ01000006; ORY64953.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2E091; -.
DR STRING; 1141098.A0A1Y2E091; -.
DR InParanoid; A0A1Y2E091; -.
DR OrthoDB; 408598at2759; -.
DR Proteomes; UP000193689; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11060; CYP57A1-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24305; CYTOCHROME P450; 1.
DR PANTHER; PTHR24305:SF85; P450, PUTATIVE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW Iron {ECO:0000256|RuleBase:RU000461}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000193689};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 507 AA; 57741 MW; 499D9F0E24FDF4A6 CRC64;
MALFSLGNFA LLIAGYIVFK VVYQVVYYRF FHPLAKFPGP FLASVTRLWI TYHNVKEDEC
HTFQELHKKH GPVIRVTPTM LLVSDATKLP EIYNRQANKS QHYITGSFGK TESLFNMQDT
KTHAHFRKIA AAPYSFSNIK KMEPLIDMRI GEWIMKLDTN FAKTGAKFDF APWAVYMAYD
IISEVGFGAP FGFIEQGKDV EGLIQGFHDG LVPFGIMARL YPFTNWVKST WMGRYLVASP
EQDSGIGTLM RFRDKLIAQR FKDIEAGTTG GRIDLLQTFI EARDEKGEPL DLDYIKAEIL
LVLLAGADTT GTAFQALMLH IMSNPSVYDR MMAEIDEGNR SGKLSSPMPQ YDEVMTHCPY
YVACVRESMR LNPSAPNIFP RLAPKGGLEL FGKFVPEGSE VTCNPWLVHR DQAIYGEDAE
EFRPERWLDA EKSRDYAKYN MGFGYGARVC LGQDIARMEL YKAPLQFFQT FKPDILNREA
PAKYLVKGGV SYFEDMWVKL ERRAAVV
//
