ID   A0A1Y2E205_9PEZI        Unreviewed;      1264 AA.
AC   A0A1Y2E205;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Ras-GAP domain-containing protein {ECO:0000259|PROSITE:PS50018};
GN   ORFNames=BCR38DRAFT_484812 {ECO:0000313|EMBL:ORY65384.1};
OS   Pseudomassariella vexata.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Pseudomassariaceae; Pseudomassariella.
OX   NCBI_TaxID=1141098 {ECO:0000313|EMBL:ORY65384.1, ECO:0000313|Proteomes:UP000193689};
RN   [1] {ECO:0000313|EMBL:ORY65384.1, ECO:0000313|Proteomes:UP000193689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 129021 {ECO:0000313|EMBL:ORY65384.1,
RC   ECO:0000313|Proteomes:UP000193689};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY65384.1}.
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DR   EMBL; MCFJ01000006; ORY65384.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2E205; -.
DR   STRING; 1141098.A0A1Y2E205; -.
DR   InParanoid; A0A1Y2E205; -.
DR   OrthoDB; 22721at2759; -.
DR   Proteomes; UP000193689; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   CDD; cd00030; C2; 1.
DR   CDD; cd05137; RasGAP_CLA2_BUD2; 1.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF60; GTPASE-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF00616; RasGAP; 1.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000193689}.
FT   DOMAIN          752..985
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          1..247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          372..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1150..1171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1183..1264
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..93
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        114..171
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..231
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1183..1209
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1221..1245
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1264 AA;  139858 MW;  AF9FC2934525587B CRC64;
     MNGILPPGMD GGTRSGGHVG RLPQGTAITL PRGGSERERG GDRSNFRTSA SRSTIRTVTP
     EPAEHGHATT DTNITQAPLD RAYGTTSPQT SPRPIPGGER RRQGVIFKEA YGGSFDSSES
     SPPQHQSTAV RARTQTMDTA LALRQQQTAA SSTTSRHRVG SLSSSGSIPF TDVDGSRVPP
     VTNVESVGYP SITPAPPPDL KITVSSSRDK KGQSSSLSNR RLIKRASSRP TSPLISPPPS
     VDSLPIPIPT DDSNKVLLLM KTLCGRMRGE VEYQSEQGGP WYRGICYIDE ERGSLLFDSG
     QSAPFHMPIV ADLRGCRVLP VDFPESGTKC LELANSKAGI ELLLRPLLAA EFDLWLAALL
     CWQQLKPGGI RLPSGRGNNS PVAGRPDLRR RGSSATGSTS SKDAAIIKVG KVMLWDKGVA
     NSPRAIVKRP STRDLRGSAT AWRRVSCILQ DNGEFKLMTE NDVTVLSVIE LSQLSRCAVQ
     QLDKSVLDET YCIAIFPIYS STSRQLSIFR PVYIALDSRV LFEVWFVLLR AFAVPDLYGI
     GAGSDQVSEI TNFETEFDGQ MFRLEKTIEV RLTEAKIRTV NPAPEQHERY GRGDRDAGSG
     NYFAEVILDG EVRARTTTQP TNNPFWREAA QFTELATALP YLSIVLKRVD GNLEGFSQQL
     QASLGLPKTG NLTEVMCGSV DIQLDKLERG KDHEQWQQIL DEKNESIGSM LVKINHQELV
     VLMTKDYEVL SDLLHKFSIG LTNQIASAMP QQLRRLAELF LNIFQVTNKS SEWLMALVEE
     EIDGLSGPNS MKKMRFSRRL KSNDSNASAS ERELLVRDMG KSLAGEANLL FRGNSLLTQA
     LECHMRRLGK DYLEEILSDK IFEINEINPD CEVDPIKVRG EDINQHWTQL MQLTNEVFEC
     IASSATKLPA ELRQILKYVR AVAEDRYGDF LRTVTYTSVS GFLFLRFICP AILNPKLFGL
     LRDNPRPKAQ RTLTLIAKGL QALGNLATFG KKESFMEPMN KFLNHQRQPF KDFIDQVCSI
     SAERNGVTLP ATYTTPITIL GRLSPISREG FPALPYLIDH PRNYAALVKL WLEAHHANDP
     SSHILEGELA QFHDACVRLQ KRSDDCMARI ESIRAAETMS ILTDDVTESL EKTSLVDHAH
     LAYVNQPAWM ENDPYRAPGS SGSEQEGGDR SIFRDLNFRS NRDGSSLRQV SDSSEISHTG
     GTLRRNGINP RQFLSGLIGG KKHKSEGHTS TPSSMREKNR DKEGGSRSML GGFSESWQSD
     NSRH
//