ID   A0A1Y2E7R0_9PEZI        Unreviewed;       703 AA.
AC   A0A1Y2E7R0;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Kinase-like domain-containing protein {ECO:0000313|EMBL:ORY67613.1};
GN   ORFNames=BCR38DRAFT_160978 {ECO:0000313|EMBL:ORY67613.1};
OS   Pseudomassariella vexata.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Pseudomassariaceae; Pseudomassariella.
OX   NCBI_TaxID=1141098 {ECO:0000313|EMBL:ORY67613.1, ECO:0000313|Proteomes:UP000193689};
RN   [1] {ECO:0000313|EMBL:ORY67613.1, ECO:0000313|Proteomes:UP000193689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 129021 {ECO:0000313|EMBL:ORY67613.1,
RC   ECO:0000313|Proteomes:UP000193689};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC   -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC   -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC       {ECO:0000256|ARBA:ARBA00038211}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY67613.1}.
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DR   EMBL; MCFJ01000004; ORY67613.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2E7R0; -.
DR   STRING; 1141098.A0A1Y2E7R0; -.
DR   InParanoid; A0A1Y2E7R0; -.
DR   OrthoDB; 144299at2759; -.
DR   Proteomes; UP000193689; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd05157; ETNK_euk; 1.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   InterPro; IPR007521; Choline_kin_N.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR   PANTHER; PTHR22603:SF93; RE24176P; 1.
DR   Pfam; PF04428; Choline_kin_N; 1.
DR   Pfam; PF01633; Choline_kinase; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000313|EMBL:ORY67613.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193689};
KW   Transferase {ECO:0000313|EMBL:ORY67613.1}.
FT   DOMAIN          160..236
FT                   /note="Choline kinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04428"
FT   REGION          1..112
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          182..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          628..655
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..56
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        69..106
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..196
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   703 AA;  79944 MW;  1398DDB65D380E73 CRC64;
     MGQTSLEALS GQVSNPSPRQ GPEDSGSSQP HHHRLDHMGE RLISQVAEWL EHERTKKQQR
     KTRRVYSHKR KSPPAEPERE RGRPEEPGEP SAVEQLTRHH RRYSIDSQSS DVSLDRLQRI
     IDDSMNALGL NSIPHYRPGM GRKSHKKRAH HLHRTASSDT EYHDGDVRVP SCDAVLDNSK
     TMSYSGGKSG EGADGTSVSS RKVDKEREDW IKFKNDVLRI AHTLRIKGWR RVPLDTGDTI
     DIERLSGALT NAVYVVTPPQ ELLNNTEGGK KAPAKLLLRV YGPQVENIID RDNELNVLKR
     LSRKKIGPRM LGTFENGRFE QFFNAITLTP AHLREPETSK QIAKRMRELH DGIELLEEEK
     DGGPAVFKNW DHWLDNTAKV VTYLDRKGRS GGLGPIRGPA DAWKERGLIC GVEWAKFEQA
     LDKYRKYLDD YYAGHKNLRD QLVFAHNDTQ YGNILRIRPD DEKSPLMSPQ NEHKQLIVID
     FEYAAANMRG HEFANHFTEW TYNYHNVTAP YACNTSRYPT LEEQRRFIKA YVEHRPQFPH
     AGSTPNLTPH DTPLGTPGLG ATTPGSSSIV DFMLDARIPP GGYKDDEKRR EEQVEQRIKE
     LLEETRLWRT ANSAQWVAWG IMQAKVPGLE QKDGPPEDAE AKGSQPAAIV SPEEQPGGAD
     EFDYLAYAHE RALLFWGDCV KMGVVKMEEL PEELRGKIKL IEY
//