ID A0A1Y2EIZ8_9PEZI Unreviewed; 575 AA.
AC A0A1Y2EIZ8;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 13-SEP-2023, entry version 19.
DE RecName: Full=tRNA modification GTPase TrmE {ECO:0008006|Google:ProtNLM};
GN ORFNames=BCR38DRAFT_12978 {ECO:0000313|EMBL:ORY71562.1};
OS Pseudomassariella vexata.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Pseudomassariaceae; Pseudomassariella.
OX NCBI_TaxID=1141098 {ECO:0000313|EMBL:ORY71562.1, ECO:0000313|Proteomes:UP000193689};
RN [1] {ECO:0000313|EMBL:ORY71562.1, ECO:0000313|Proteomes:UP000193689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 129021 {ECO:0000313|EMBL:ORY71562.1,
RC ECO:0000313|Proteomes:UP000193689};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. TrmE GTPase family.
CC {ECO:0000256|ARBA:ARBA00011043}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY71562.1}.
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DR EMBL; MCFJ01000001; ORY71562.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2EIZ8; -.
DR STRING; 1141098.A0A1Y2EIZ8; -.
DR InParanoid; A0A1Y2EIZ8; -.
DR OrthoDB; 5478664at2759; -.
DR Proteomes; UP000193689; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR CDD; cd04164; trmE; 1.
DR CDD; cd14858; TrmE_N; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.120.430; tRNA modification GTPase MnmE domain 2; 1.
DR HAMAP; MF_00379; GTPase_MnmE; 1.
DR InterPro; IPR031168; G_TrmE.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR018948; GTP-bd_TrmE_N.
DR InterPro; IPR004520; GTPase_MnmE.
DR InterPro; IPR027368; MnmE_dom2.
DR InterPro; IPR025867; MnmE_helical.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42714; TRNA MODIFICATION GTPASE GTPBP3; 1.
DR PANTHER; PTHR42714:SF2; TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF12631; MnmE_helical; 1.
DR Pfam; PF10396; TrmE_N; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF116878; TrmE connector domain; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000193689};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 64..187
FT /note="GTP-binding protein TrmE N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10396"
FT DOMAIN 190..572
FT /note="MnmE helical"
FT /evidence="ECO:0000259|Pfam:PF12631"
FT DOMAIN 289..402
FT /note="G"
FT /evidence="ECO:0000259|Pfam:PF01926"
SQ SEQUENCE 575 AA; 62429 MW; 7986959A7C0FAB35 CRC64;
MLRCLARGAS QFLRSRLPYP PVTKAGVSSG VLVTPRCPTA SLCLGLRVRN GERMFLTSAQ
KNDTIYALST AQGKAGIAVI RISGPSCKTV YESLCPSKAI PKPRYAGVRT LFHPESSETN
VIDSNAMVLY LSGPKTVTGE DVLELHVHGG NATVKAVLSA IAASRTRGRV RYAEPGEFTK
RAFLNDRLDL AQVEALSDML SAETEQQRRA AVHGTSGALG RIYEGWRQKL LKARAEIEAI
IDFSEDQHFD DSPLDLLANV SRQVEQMLSS IEMHETASQR SELLRNGIKI ALLGPPNAGK
SSLMNQIVGR EASIVSGEAG TTRDIVEAHL DIRGYLCTFA DTAGFRSVKS VEGSGFDQAG
HIIGTVEQEG IRRARSKALE SDLVVVLASI EQVQSGEYMI NYDSETLGLL ISVGRGIVVV
NKRDVLPEEE LEDLIEDFQV SVLDKIKGLS ASPILVSCKQ ARDHNGTDIN PRGIDGVVTG
LVQLFTDMTL LPVDQQGLHG VTERQRQLLV QCRKHLEDYV GNTTSDDAID ELKFVVAAED
LRYAANCLAR ITGHGESGDV EEVLGVIFEK FCVGK
//
