ID A0A1Y2EQM0_9BASI Unreviewed; 615 AA.
AC A0A1Y2EQM0;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 13-SEP-2023, entry version 16.
DE SubName: Full=Xanthine/uracil permease {ECO:0000313|EMBL:ORY73839.1};
GN ORFNames=BCR35DRAFT_306949 {ECO:0000313|EMBL:ORY73839.1};
OS Leucosporidium creatinivorum.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Leucosporidiales; Leucosporidium.
OX NCBI_TaxID=106004 {ECO:0000313|EMBL:ORY73839.1, ECO:0000313|Proteomes:UP000193467};
RN [1] {ECO:0000313|EMBL:ORY73839.1, ECO:0000313|Proteomes:UP000193467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=62-1032 {ECO:0000313|EMBL:ORY73839.1,
RC ECO:0000313|Proteomes:UP000193467};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY73839.1}.
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DR EMBL; MCGR01000044; ORY73839.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2EQM0; -.
DR STRING; 106004.A0A1Y2EQM0; -.
DR InParanoid; A0A1Y2EQM0; -.
DR OrthoDB; 911690at2759; -.
DR Proteomes; UP000193467; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000193467};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 96..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 547..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..615
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 64852 MW; 940FD96C8044C363 CRC64;
MSSIISAQPQ AAHQLDPHHV PADHDDFDAE GHGDGAAKLP SLAQIKRKLT TKQGWLGDYD
FGFLCMPQLP FSLGKGKKKT RPTPFYALEQ EMPISLALVC GLQHALAMLA GLITPPIIFA
NQLGFNASQQ NQMVAVSLIA SGILSALQMS RFPIPFTNKK YWLGTGLITV VGTSFATLST
ASAIFTSLYA DGTCPSSVVD GVTVRGNCPE AYGALIGTSC LCSLLEMGLA FVSPKVLKRI
FPPVVTGTVI LLIGASLVGE SGFLNWGGGS GNCHSRPETG FFALCPNINA PRAYQWGDAR
YIGLGFLSYV TIIIVEFFGS PAMKSASIIM GLLVGCIVAA PLGYTSASSI TSAPAITFLW
VHTFPLRIHG PSILPMLCVY ISLAMEATGD ITASSEASRQ PVEGRLFDSR VQGGILADGV
NGCISGLMMN PPVSIFAQNN GVISITRCAN RFAGYLCSAI LVLFGVLAKI SGVFLAIPAP
VLGGVTTFLF SSVAVSGLKV LSLTSFTRRD RMILASALSL GLGNLLVDDW SSYIFTYAGP
NAALKGFMNS IIIVLSTPFL IAGIVASLLN ALLPADPDSA PTHSDEDEDD ELERVEAAKP
ARRVSSSVDD DIKQA
//
