ID A0A1Y2F1U4_PROLT Unreviewed; 701 AA.
AC A0A1Y2F1U4;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=mRNA 3'-end-processing protein RNA14 {ECO:0000256|RuleBase:RU369035};
GN ORFNames=BCR37DRAFT_119090 {ECO:0000313|EMBL:ORY77677.1};
OS Protomyces lactucae-debilis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Taphrinomycetes;
OC Taphrinales; Protomycetaceae; Protomyces.
OX NCBI_TaxID=2754530 {ECO:0000313|EMBL:ORY77677.1, ECO:0000313|Proteomes:UP000193685};
RN [1] {ECO:0000313|EMBL:ORY77677.1, ECO:0000313|Proteomes:UP000193685}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12-1054 {ECO:0000313|EMBL:ORY77677.1,
RC ECO:0000313|Proteomes:UP000193685};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the cleavage factor IA (CFIA) complex, which is
CC involved in the endonucleolytic cleavage during polyadenylation-
CC dependent pre-mRNA 3'-end formation. {ECO:0000256|RuleBase:RU369035}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369035}.
CC Cytoplasm {ECO:0000256|RuleBase:RU369035}. Note=Nucleus and/or
CC cytoplasm. {ECO:0000256|RuleBase:RU369035}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY77677.1}.
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DR EMBL; MCFI01000019; ORY77677.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2F1U4; -.
DR STRING; 56484.A0A1Y2F1U4; -.
DR OMA; PKRQYFK; -.
DR OrthoDB; 23291at2759; -.
DR Proteomes; UP000193685; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006378; P:mRNA polyadenylation; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.40.1040; -; 1.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR045243; Rna14-like.
DR InterPro; IPR008847; Suf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR19980:SF0; CLEAVAGE STIMULATION FACTOR SUBUNIT 3; 1.
DR PANTHER; PTHR19980; RNA CLEAVAGE STIMULATION FACTOR; 1.
DR Pfam; PF05843; Suf; 1.
DR SMART; SM00386; HAT; 7.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|RuleBase:RU369035};
KW mRNA processing {ECO:0000256|RuleBase:RU369035};
KW Nucleus {ECO:0000256|RuleBase:RU369035};
KW Reference proteome {ECO:0000313|Proteomes:UP000193685};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 31..64
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 403..565
FT /note="Suppressor of forked"
FT /evidence="ECO:0000259|Pfam:PF05843"
FT REGION 655..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..701
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 701 AA; 78883 MW; D19CAD331D53D93A CRC64;
MSASPARKGD RLEADTAGIL EDRIEENKYD FEAYLSLARF QRDKAKLDEA REAYEKLLRL
LPACASVWIE YADLEASASE FQRVEQIFTK CLQSVLNVEL WSYYLAYIKR MNDLSTGGAQ
ARATVAQAYE FVLSHVGFDV KAGSLWLDYI QFIRRTYQRA VVIPLNSVEQ LWREYDSFEN
TVSKATARKF LSERSPAYMT ARACARELLQ MTEPLRQATF PALPTRNAAE NSYVTSWRRW
IGWEKQDPLE LDDPKQLQSR VKYAYKQCLQ FCRFFPEMWF DAAFYAASIG ENDLALYQEG
LEANPTSWLL GFAYAEAEEL AKHGDVVKGT FDKLISSNKE AMSELESQID EAAQSAGAEK
KLKIGAEDDD DSDEDEEPGQ DMAALANVEE LRSRLKRYAE EGTTAYIMYM RAMRRLEGIK
AARAIFARAI KESKHTWHIY VASALMEHHC SKDSNVAVKI FGRGLKHHSE NPDFVLEYLN
FLIAIKDDTN ARALFEQTTA KLEGHKAVKL FERFYEYESM YGDLITAQKM ATRMSEIDPS
ANVLTRFGKR FTFSDCDPIA SRDLGLTRLP AATGPFPPPP PPLSLPPFAG MSMLHGDGIH
AAVRPPPAPV PPAVLDLLTR LPPSSAMDSS RQFHAKALVD VVASLDLEAY QAKQQKQAKS
ATSNATKRKA AAAAVVPPPE ELRALGKHND AKDIYNAKRR A
//
