ID A0A1Y2FBK3_9BASI Unreviewed; 447 AA.
AC A0A1Y2FBK3;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Delta-12-fatty acid desaturase {ECO:0000313|EMBL:ORY81298.1};
GN ORFNames=BCR35DRAFT_304170 {ECO:0000313|EMBL:ORY81298.1};
OS Leucosporidium creatinivorum.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Leucosporidiales; Leucosporidium.
OX NCBI_TaxID=106004 {ECO:0000313|EMBL:ORY81298.1, ECO:0000313|Proteomes:UP000193467};
RN [1] {ECO:0000313|EMBL:ORY81298.1, ECO:0000313|Proteomes:UP000193467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=62-1032 {ECO:0000313|EMBL:ORY81298.1,
RC ECO:0000313|Proteomes:UP000193467};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY81298.1}.
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DR EMBL; MCGR01000023; ORY81298.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2FBK3; -.
DR STRING; 106004.A0A1Y2FBK3; -.
DR InParanoid; A0A1Y2FBK3; -.
DR OrthoDB; 4215at2759; -.
DR Proteomes; UP000193467; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProt.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR021863; FAS_N.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF35; OMEGA-3 FATTY ACID DESATURASE FAT-1; 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF11960; DUF3474; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000193467};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 69..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..82
FT /note="Fatty acid desaturase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11960"
FT DOMAIN 111..395
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 447 AA; 50041 MW; D94602552CB1B9EC CRC64;
MSAASTLRQR VPVDKVKSVA APASDSSDSG DELLTYGDFP PFTPPSFTIK EILGAIPAHC
FERSALRSGA YVVGDFTMVA ALMYAASFIE PALGFQGQVL DGYAGLAAKW AAWSTYWVLA
GFVYTGIWII AHECGHQAFS TSKTINNTMG LILHSFVLVP YHSWRISHGK HHAATGHMTR
DEVFVPATRS EKCANEGKGT GRKVMIGGME LEELFDDSPL YRLYGLFVQQ LFGWPAYLFN
NASGQAWYPK GTNHFDPNSL IFDARHRQQI LISDAALLTM GALLTAFGHY AGGLSAVGKY
YFVPYLMVNH WLVFITYLQH TDPMLPHYRA GEWNFQRGAL CTIDRNLMGP VGPYLMHGIT
ETHVSHHICS KIPHYHAWEA TEALKEFLGE HYVSTDENMW VSLWKSYRQC RFVEDEGEVV
FYKDQYGRTS RQVVYESLPS DSGVDVN
//
