ID A0A1Y2FGG2_PROLT Unreviewed; 621 AA.
AC A0A1Y2FGG2;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 13-SEP-2023, entry version 23.
DE RecName: Full=U3 small nucleolar RNA-associated protein 25 {ECO:0000256|ARBA:ARBA00015422, ECO:0000256|RuleBase:RU365070};
DE Short=U3 snoRNA-associated protein 25 {ECO:0000256|RuleBase:RU365070};
GN ORFNames=BCR37DRAFT_413166 {ECO:0000313|EMBL:ORY83030.1};
OS Protomyces lactucae-debilis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Taphrinomycetes;
OC Taphrinales; Protomycetaceae; Protomyces.
OX NCBI_TaxID=2754530 {ECO:0000313|EMBL:ORY83030.1, ECO:0000313|Proteomes:UP000193685};
RN [1] {ECO:0000313|EMBL:ORY83030.1, ECO:0000313|Proteomes:UP000193685}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12-1054 {ECO:0000313|EMBL:ORY83030.1,
RC ECO:0000313|Proteomes:UP000193685};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC processing, specifically at sites A0, A1, and A2.
CC {ECO:0000256|ARBA:ARBA00002883, ECO:0000256|RuleBase:RU365070}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC composed of at least 40 protein subunits and snoRNA U3.
CC {ECO:0000256|RuleBase:RU365070}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU365070}.
CC -!- SIMILARITY: Belongs to the UTP25 family.
CC {ECO:0000256|ARBA:ARBA00009223, ECO:0000256|RuleBase:RU365070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY83030.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MCFI01000008; ORY83030.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2FGG2; -.
DR STRING; 56484.A0A1Y2FGG2; -.
DR OMA; KYFRQTI; -.
DR OrthoDB; 5473087at2759; -.
DR Proteomes; UP000193685; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010678; UTP25.
DR PANTHER; PTHR12933; ORF PROTEIN-RELATED; 1.
DR PANTHER; PTHR12933:SF0; U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG; 1.
DR Pfam; PF06862; UTP25; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365070};
KW Reference proteome {ECO:0000313|Proteomes:UP000193685};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU365070};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU365070};
KW rRNA processing {ECO:0000256|RuleBase:RU365070}.
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..53
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 621 AA; 70340 MW; 3F3B610E00460B4F CRC64;
MKRDEAEEPR QKKRRLQEPE VDREATPEDE DVVGNEPEAE EEEEAEEAVV EQDDVSPLDP
FESHFAAPDA ELLEKLVSQV GKAKIQAKMT QTGDCKVYCN EPEEALAKHR INLQKPESLH
VKQRLSNIIP KLQLKEATQA SFVQQLLCYK DISYSATTHK TLPHLRGACA AHILNHIFKT
RDRILKNNGK LAQHRDDELE LRDQSFTRPK VLILMPTRNA AFLFVNQLIA LAGAESIENR
KRFNDNFGAA DKDPVKSSTK PEDFKAFFEG NTDDAFRLGI KFTRKTIKLF SQFYASDIII
ASPLGLRMVI GDPAQKKVDY DFLSSIELLL LDSCDGLAMQ NWEHVAFALE HLNLIPKESH
GCDYARVRNW CLEEKSKYLR QTILLSAYEF PEQRQVFQSL VNVAGQVRFR PTYTGKIANV
QAKQIFSRLT CDATNPASEP DARYKHFATA LLPRIKKLAV TGSAAVSASP EEATSHCAGI
LLVVPSYFDF LRVRNCLNAE EVSFEAISEY AKSSQLSRSR ALFAAGRCQV LVVTERLQFY
RRYAYRGAKR VMFYQLPEHA DFYTELARSA IETAAVLGND ASDVEVRAVF SHFDALRLER
IVGSQRIARM LQSKDASFEF S
//
