ID   A0A1Y2FM79_PROLT        Unreviewed;       457 AA.
AC   A0A1Y2FM79;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Autophagy-related protein 17 {ECO:0000256|ARBA:ARBA00013806, ECO:0000256|RuleBase:RU368080};
GN   ORFNames=BCR37DRAFT_258690 {ECO:0000313|EMBL:ORY85081.1};
OS   Protomyces lactucae-debilis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Taphrinomycetes;
OC   Taphrinales; Protomycetaceae; Protomyces.
OX   NCBI_TaxID=2754530 {ECO:0000313|EMBL:ORY85081.1, ECO:0000313|Proteomes:UP000193685};
RN   [1] {ECO:0000313|EMBL:ORY85081.1, ECO:0000313|Proteomes:UP000193685}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12-1054 {ECO:0000313|EMBL:ORY85081.1,
RC   ECO:0000313|Proteomes:UP000193685};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Autophagy-specific protein that functions in response to
CC       autophagy-inducing signals as a scaffold to recruit other ATG proteins
CC       to organize preautophagosomal structure (PAS) formation. Modulates the
CC       timing and magnitude of the autophagy response, such as the size of the
CC       sequestering vesicles. Plays particularly a role in pexophagy and
CC       nucleophagy. {ECO:0000256|RuleBase:RU368080}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU368080}.
CC       Preautophagosomal structure membrane {ECO:0000256|RuleBase:RU368080};
CC       Peripheral membrane protein {ECO:0000256|RuleBase:RU368080}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004170}.
CC   -!- SIMILARITY: Belongs to the ATG17 family.
CC       {ECO:0000256|ARBA:ARBA00006259, ECO:0000256|RuleBase:RU368080}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY85081.1}.
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DR   EMBL; MCFI01000005; ORY85081.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2FM79; -.
DR   STRING; 56484.A0A1Y2FM79; -.
DR   OMA; THVWRAN; -.
DR   OrthoDB; 1940609at2759; -.
DR   Proteomes; UP000193685; Unassembled WGS sequence.
DR   GO; GO:0034045; C:phagophore assembly site membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   InterPro; IPR007240; Atg17.
DR   InterPro; IPR045326; ATG17-like_dom.
DR   PANTHER; PTHR28005; AUTOPHAGY-RELATED PROTEIN 17; 1.
DR   PANTHER; PTHR28005:SF1; AUTOPHAGY-RELATED PROTEIN 17; 1.
DR   Pfam; PF04108; ATG17_like; 1.
PE   3: Inferred from homology;
KW   Autophagy {ECO:0000256|RuleBase:RU368080};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU368080};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193685}.
FT   DOMAIN          12..407
FT                   /note="Autophagy protein ATG17-like"
FT                   /evidence="ECO:0000259|Pfam:PF04108"
FT   COILED          144..171
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          260..287
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          373..400
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   457 AA;  50908 MW;  1888EB46398CD616 CRC64;
     MLSHFHAAKK ALSRGTLSCH KADQLTKDTE ANLQNAIHLQ QHITHLREAL HAQIHTLSLL
     AHTFRGEARA GQTLFDGTLR ELDGLDGQLN TALAMLKRAR LPRVLVQPSA QQLESVSSGS
     SLETGNSAIT RSKTLFDFAD DQGIEQLKGG LRQAVDDLQE SQEQLASLYA TFDGHVRALD
     KTLALLPTDP ILLLPQISQS HRQGDALSLS ATAETCRAQQ AEHLVSLAEL LLSLSQHYDH
     TQTLSTSSAA LPQDARAELR EVVEEDAVQL EDVLAEMDER VVDLEEDLTF VTNHVAALQQ
     VTQQLEEAFS VFEALDIDTP VHTLDDIRAT RTTREMTLDM RREQLLGLAE QFTQFSRSYD
     ALLLEIDRRA QHDAAVDALM EQTQRQLEQL QQQEMAERAA FLSMHGASLP EDIWHGIRDS
     PAGWVMQREQ DAQTTPVLSQ SVLQAARSRH AQWSQSR
//