ID   A0A1Y2FMJ2_PROLT        Unreviewed;       611 AA.
AC   A0A1Y2FMJ2;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Polynucleotide 5'-hydroxyl-kinase GRC3 {ECO:0000256|ARBA:ARBA00019824};
DE   AltName: Full=Polynucleotide 5'-hydroxyl-kinase grc3 {ECO:0000256|ARBA:ARBA00018706};
GN   ORFNames=BCR37DRAFT_378475 {ECO:0000313|EMBL:ORY84446.1};
OS   Protomyces lactucae-debilis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Taphrinomycetes;
OC   Taphrinales; Protomycetaceae; Protomyces.
OX   NCBI_TaxID=2754530 {ECO:0000313|EMBL:ORY84446.1, ECO:0000313|Proteomes:UP000193685};
RN   [1] {ECO:0000313|EMBL:ORY84446.1, ECO:0000313|Proteomes:UP000193685}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12-1054 {ECO:0000313|EMBL:ORY84446.1,
RC   ECO:0000313|Proteomes:UP000193685};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
CC       {ECO:0000256|ARBA:ARBA00011003}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY84446.1}.
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DR   EMBL; MCFI01000006; ORY84446.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2FMJ2; -.
DR   STRING; 56484.A0A1Y2FMJ2; -.
DR   OrthoDB; 5480745at2759; -.
DR   Proteomes; UP000193685; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR045116; Clp1/Grc3.
DR   InterPro; IPR032319; CLP1_P.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12755; CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; 1.
DR   PANTHER; PTHR12755:SF3; POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9; 1.
DR   Pfam; PF16575; CLP1_P; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193685};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          243..428
FT                   /note="Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop"
FT                   /evidence="ECO:0000259|Pfam:PF16575"
FT   REGION          34..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..63
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   611 AA;  65790 MW;  86DAFD397EBA4FCC CRC64;
     MKRKGDAHQL SAFAAKKLAL EEAQAAAALA LAANASDDPV ETTSDLDAES PGQELSAAQS
     DGSASELEDG MDTGVNRFAA LASSTGQSSV HPSREGFVAA AGQQRPLPAT IEEEEGSLRV
     ELPAFEVISV RGRFLLVVKS GSLCLLGARL GRMNYAILVE IPESESWPVS AAETGSNEPV
     TFLMHPCHDG IPRVLAHYPQ GRALFPISSE RLKSSLLGYG PEQYKEENLA WQDKPGDLTF
     FTGPKNSGKS TWARRRSNKA LSSGYPVLYI DLDPGQPQFS PPGIMSAYLL MTPAHFMLST
     GPIWKRPPQH LRSHWIGETS AKEDPSHYFE CALDLIRIVE RYPQAVVTIN TPGWVKGTGL
     ELLSSIIAAS LQALSDTRIH VLHLGHSDLQ RHLPEGVSNE AMPAPLPTDA VTMSAADART
     LNLLTYFHRS GDGWQTGPLA GTHTWVTSYD SDEAGIHGIA ILRESLQPLD LIAAINGTVM
     ALVEVDKSLL HGPLPRTQHG LAYLENDGAP IPPASSNCIA LAIVAGLDLA QRKIHLISPI
     TAAQLDKYSR KDAQRALLLV SGGIEVPAAA MFGNATGIRG ERPYVTQKAG EGVGWQAWHV
     RRNIGRRMRQ T
//