ID A0A1Y2FNR4_PROLT Unreviewed; 377 AA.
AC A0A1Y2FNR4;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Translation initiation factor eIF2B subunit alpha {ECO:0000256|ARBA:ARBA00044208};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit alpha {ECO:0000256|ARBA:ARBA00044236};
GN ORFNames=BCR37DRAFT_377339 {ECO:0000313|EMBL:ORY85642.1};
OS Protomyces lactucae-debilis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Taphrinomycetes;
OC Taphrinales; Protomycetaceae; Protomyces.
OX NCBI_TaxID=2754530 {ECO:0000313|EMBL:ORY85642.1, ECO:0000313|Proteomes:UP000193685};
RN [1] {ECO:0000313|EMBL:ORY85642.1, ECO:0000313|Proteomes:UP000193685}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12-1054 {ECO:0000313|EMBL:ORY85642.1,
RC ECO:0000313|Proteomes:UP000193685};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY85642.1}.
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DR EMBL; MCFI01000004; ORY85642.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2FNR4; -.
DR STRING; 56484.A0A1Y2FNR4; -.
DR OMA; IREMQTH; -.
DR OrthoDB; 51607at2759; -.
DR Proteomes; UP000193685; Unassembled WGS sequence.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.1070; Translation initiation factor eIF-2B, N-terminal domain; 1.
DR InterPro; IPR042528; elF-2B_alpha_N.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR45860; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA; 1.
DR PANTHER; PTHR45860:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA; 1.
DR Pfam; PF01008; IF-2B; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:ORY85642.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000193685}.
SQ SEQUENCE 377 AA; 41035 MW; 29ED8E10D1C4A25B CRC64;
MAPVRPSRLS RVDTSIDSPN GSFDVLAIYR DHLERDPDIT MPLAAISALL EVLTKTNAST
VSEFTDILKR GKRILIDAVP NAYSLQAGCD IFEAFIGKSL RDVEDFDETK AHLVANGRLF
ISRAREARVK IAEIGAKFVK DGSTVLIHSY SRVVLAVLTR AAEENRRFRV FITESRPNGS
GLKSKRVLER YGIPTCMLLD VAVGYAMPLC DMVLVGAEGV VENGGLINQI GTQNVAALAK
REGKPFYCVA ESHKFVRIYP LSQFDLNKSD PVLEFSDPPS RSQAGSALGS ALGTPALRSS
EDAFAKAPPG NGFFEEGIKV TSSSADVRNE HVMSLDDICN NPSLDLTPPE MITALVTDLG
VLNPMSGVSE ELIRLWY
//
