ID A0A1Y2FP83_9FUNG Unreviewed; 1298 AA.
AC A0A1Y2FP83;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=P-loop containing nucleoside triphosphate hydrolase protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LY90DRAFT_394932 {ECO:0000313|EMBL:ORY85812.1};
OS Neocallimastix californiae.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Neocallimastigomycetes; Neocallimastigales;
OC Neocallimastigaceae; Neocallimastix.
OX NCBI_TaxID=1754190 {ECO:0000313|EMBL:ORY85812.1, ECO:0000313|Proteomes:UP000193920};
RN [1] {ECO:0000313|EMBL:ORY85812.1, ECO:0000313|Proteomes:UP000193920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G1 {ECO:0000313|EMBL:ORY85812.1,
RC ECO:0000313|Proteomes:UP000193920};
RG DOE Joint Genome Institute;
RA Haitjema C.H., Gilmore S.P., Henske J.K., Solomon K.V., De Groot R.,
RA Kuo A., Mondo S.J., Salamov A.A., Labutti K., Zhao Z., Chiniquy J.,
RA Barry K., Brewer H.M., Purvine S.O., Wright A.T., Boxma B., Van Alen T.,
RA Hackstein J.H., Baker S.E., Grigoriev I.V., O'Malley M.A.;
RT "A Parts List for Fungal Cellulosomes Revealed by Comparative Genomics.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY85812.1}.
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DR EMBL; MCOG01000003; ORY85812.1; -; Genomic_DNA.
DR STRING; 1754190.A0A1Y2FP83; -.
DR OrthoDB; 3295317at2759; -.
DR Proteomes; UP000193920; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18597; ABC_6TM_YOR1_D1_like; 1.
DR CDD; cd18606; ABC_6TM_YOR1_D2_like; 1.
DR CDD; cd03250; ABCC_MRP_domain1; 1.
DR CDD; cd03244; ABCC_MRP_domain2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR PANTHER; PTHR24223:SF443; MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000193920};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 132..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 703..725
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 750..774
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 842..863
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 96..378
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 423..645
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 714..989
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1025..1260
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 658..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1298 AA; 146894 MW; 7EA2AF5AA62A8D90 CRC64;
MFSKKEYPIP NEPKPSPYTH ANPISRLLYI WQNEIFNIGY KRPIEENDIY LLDPKFKEEQ
NERKFYEKWD KAIDKKGKGN IVKTLLKVFG AKWISAGLFK VVSDLCNTFS PVFLEALLNH
LTEREEGKDH EIYKGWLFVG CIFLLQILAT LFTNLYMQIV SEVGLSVRST LVGVIYRKSL
KLSNKERQSI GDGQIVNLVS SDSNRFERLI MTLHYLWSGP LQLIIILVLL IRSLGFWSLI
GFSIFVIVIP LQGVIMKLSA RLRQKTAKLT DQRVKKTQEI LGSMRIIKFF GWENSFLNVL
SKLRTNELNH TKKAIYLRAE TSTIFSIAPF LASALTFIAY SAAGNPLTSA KVFSCIAFFN
KLRAPLAILP NTFSQLTDAW VSVKRLSRLL NAKELDDLPE IDKNNEYAIV VKDGEFNWES
ISLSDESVNL KKKPVESFKL HDININIKRG SLTAVVGAVG SGKSSLINAI IGEMKREGGK
IIHGGTFSYC SQQPWIQNAT IKDNILFGKE YNEELYDSVI ENCCLSHDLE VFQDGDMTEI
GERGITLSGG QKQRINLARA VYYDSDIILM DDPLSAVDAH VCRDLFDNCI TGLLEGKTRI
LVTHQLHVLP DVDYIIVMKG GRIEEQGDYD ELLKKNGEFA RLMRTYGGID ESEDAKAKAA
AKKKEKKETK KETKKEEKKK GKALMTQEER ATGSVDSKVY KDYIIAAGGI FCAALVMLVV
VIIQLCKLGN DMWLVYWTKD QFGLTTNTYI LVYLVWNLVQ VLLTLFYSVF MAIIGIRAAR
RIHRNAISRV LKAPVSFFDT TPLGRIINRF SKDQDSLDGM LFMAIQMLLT DVANTITTLC
LMIYAAPLFG IALVPLLILY YFVQQYYRST SRELKRIESI TRSPIYTNIT ETLQGLPTIR
AYDAQERFIT YNQGLIDRNN RSQFLQLTAQ RWLSVRLESI GSFIVLFDGV AGLLLKESLS
AALLGLSLTY SLQVTQSLNG VVRSFSDLEV NMNSAERLLY YANEIETEDQ KGLQPPEDWP
SKGKIEFRNM TMKYAPDLPP VLRNINLDIK SFENIGVVGR TGAGKSSIVM TLFRLVEPEL
GSVIKIDDID ILDLKLSELR RRIAIIPQEP TLFSGTIRFN MDPFDEHTDQ EIWDALENAG
LKQTISELDN KLESEVRANG ENFSVGQRQL LCLARAMIRD SRILVMDEAT ASVDIETDAV
IQKALRTKFS NVTVLTIAHR LNTIIDYDKI LVLNKGEVLE YDTPKNLLFE TNENGELVPC
TSTEFSKLVD ETGPVNAALL RQTALDKYYR DNNIATTN
//
