ID   A0A1Y2FR70_PROLT        Unreviewed;       632 AA.
AC   A0A1Y2FR70;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Alpha-actinin {ECO:0000313|EMBL:ORY86077.1};
GN   ORFNames=BCR37DRAFT_376599 {ECO:0000313|EMBL:ORY86077.1};
OS   Protomyces lactucae-debilis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Taphrinomycetes;
OC   Taphrinales; Protomycetaceae; Protomyces.
OX   NCBI_TaxID=2754530 {ECO:0000313|EMBL:ORY86077.1, ECO:0000313|Proteomes:UP000193685};
RN   [1] {ECO:0000313|EMBL:ORY86077.1, ECO:0000313|Proteomes:UP000193685}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12-1054 {ECO:0000313|EMBL:ORY86077.1,
RC   ECO:0000313|Proteomes:UP000193685};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY86077.1}.
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DR   EMBL; MCFI01000003; ORY86077.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2FR70; -.
DR   STRING; 56484.A0A1Y2FR70; -.
DR   OMA; CYEGVEV; -.
DR   OrthoDB; 2872403at2759; -.
DR   Proteomes; UP000193685; Unassembled WGS sequence.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProt.
DR   GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR   Gene3D; 1.20.58.60; -; 2.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR   Gene3D; 1.10.238.10; EF-hand; 2.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014837; EF-hand_Ca_insen.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR   PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR   Pfam; PF00307; CH; 2.
DR   Pfam; PF08726; EFhand_Ca_insen; 1.
DR   SMART; SM00033; CH; 2.
DR   SMART; SM01184; efhand_Ca_insen; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   SUPFAM; SSF46966; Spectrin repeat; 2.
DR   PROSITE; PS50021; CH; 2.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193685};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          9..116
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          125..230
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          484..519
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
SQ   SEQUENCE   632 AA;  71820 MW;  1FC74F4B3BBB0E4E CRC64;
     MNDELTWVDV QHRTFTTWLN TQLSKSDEHV AITNLATGLS DGVHLIKLLE SISEEKIGRY
     NRKPKLRVQK AENVNIALDF IRSKNISLTN IGAEDIIDGN LKLICGLLWM LILRFTISDI
     NVDGLTAKEG LLLWCQRKTQ GYVGVEVRNF TTSWTDGLAF CSLLHRYRPD LLEFSKLDAS
     DAVANMSLAF DLAEKHIGIH KLLRVEDICT SVPDERSVMT YVAQFFHAFS HLDRVEAAGR
     RVVVFAETVQ SCWTLQHDYE KRAAALFEAL EEVTKNWHAT SFDGTYEDAK HQSTALVNFK
     ALQKRAWTRE KLSLESLFGD IETKLKTYKM ASYVPPSHLA VHQIGRHWES FIEAEGMRSR
     LINKQMRKVK EDLRINFADK ANDFAAMLKT LSVHLSSMTG ELDQQLSDTA YLVEHIAPLQ
     EALGDLHEAA AQCERANVEE NDHTIYTYDD MEYEFKLAHE AITKRYQFLE NQIIAKSKTN
     ITPAHLEEID NVFRHFDKSS SNKLQENELV AALASLGLTY DDAEMQNIVA EIGDESGKTG
     WEGFLNFMID ELEDQRTPEQ VLLAFREVAD SKAYVTELDL RSSQLPESTV DFLVKSLPPV
     PSTELEPEDT GQIGLDYVQF MEGLLFKAVH TT
//