ID A0A1Y2FRI6_9BASI Unreviewed; 2211 AA.
AC A0A1Y2FRI6;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=G-protein alpha subunit-domain-containing protein {ECO:0000313|EMBL:ORY85325.1};
GN ORFNames=BCR35DRAFT_324674 {ECO:0000313|EMBL:ORY85325.1};
OS Leucosporidium creatinivorum.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Leucosporidiales; Leucosporidium.
OX NCBI_TaxID=106004 {ECO:0000313|EMBL:ORY85325.1, ECO:0000313|Proteomes:UP000193467};
RN [1] {ECO:0000313|EMBL:ORY85325.1, ECO:0000313|Proteomes:UP000193467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=62-1032 {ECO:0000313|EMBL:ORY85325.1,
RC ECO:0000313|Proteomes:UP000193467};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY85325.1}.
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DR EMBL; MCGR01000016; ORY85325.1; -; Genomic_DNA.
DR STRING; 106004.A0A1Y2FRI6; -.
DR InParanoid; A0A1Y2FRI6; -.
DR OrthoDB; 2788168at2759; -.
DR Proteomes; UP000193467; Unassembled WGS sequence.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR36100; BUD SITE SELECTION PROTEIN 4; 1.
DR PANTHER; PTHR36100:SF1; BUD SITE SELECTION PROTEIN 4; 1.
DR Pfam; PF00503; G-alpha; 1.
DR Pfam; PF13023; HD_3; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000193467};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT DOMAIN 1547..1662
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 162..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 274..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..641
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 848..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1060..1093
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1155..1236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1413..1453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1693..1728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1795..1818
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1868..1908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..365
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..705
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..764
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..824
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 848..880
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..907
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 948..970
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1013
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1213..1236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1699..1728
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1797..1813
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2211 AA; 237361 MW; 353F774AE6CA7C58 CRC64;
MTSSLPSFAS PDEQGMLGFF HTLERLKTNK RTGWVNQNIR QPESIADHMY RMAMMALVIP
ESAGPRLDIS KCVMMSLVHD IAEADVGDIT PEHASGVTKE QKLQLEAAAM DRILSLLGHP
SIASLRVKSL WEEYESRETP EAKFVKDLDL FELAVQGVEY ENSWSNDAPP GPRAAGEETR
ESNKQTNAQR RQLPLNSSNS PSRVAQLGTE LQLNLLDYIS KPPSTTPSPF NQLEPSSSSN
SNGSGSANMA SPAADLSNRA SMPALASSPL VAGAEGGAQA IGVRRRESRS FKTMSTGSLV
SNSPFTKRLG GVTSPTSPQA PSTGLYSASR IPTANSNSSR SPAVQRRTSG SRKVSGEEEG
PVKENFIPRK LSSEFNQQQD EAKPLPTPRS RSTSPSVPFR PVRHHTSSSS SSGIPTASNS
TASALGSAGA PFKPSRPTFL TRQSREELVE GEPRRSSSSY AAVRKNGLVS SSPFVTKSTS
PSSIPAPLPV SATATLDSSP DLVQALYEIA PLSHESAPFS WSYNDQQDDL PQQQPLRHKD
STSAIALGAR PGGGPGPSSA GERRIAGSSV PPPNTPPHQR TASYSGSPSP SSALSPQRRG
MKGPRAPTPV EQYGGRMMGD ETETEAEDLG RTLRRQPSGK TVTWAATEEV LEFEVDDRRA
SGVSTASTLS EDSGRYYGGG GGGDESYEEE HSGFEEGGSV EVHDVDVEST DDEESVVSGA
STVEDMIGEI DDFMEESFDD IDVFSPSQID PEGFQQSPQP QRHQQFVVEE EEPEPTTPTT
PTDATTSSTA GYREYQTLPG PSSAFSTSSN SQVSTGTSDD ADDATSLSSY DDDEAEALKY
AREQILIRSQ ASSSPNLASI PTMRSPLPSP PTTSTATLGA PFSLAPPVAQ ATADSSNRDS
TFSLPDIPGT SPFMGFEDDG AAGSVVTLDM ERQRVPATQP LSPRAPPAQS TPSSSRITDP
RASFVSTGAD SPILSAFGRA SPPPLHSPRA QPQQQQQLVN PSSPDAAQLS RQASIVNSDV
SSYVPSDVGS WFGSMSSGGG AGSLLIGRDR LQRKMKEHEA ILGSGVSSPA LEPGRFPTEA
SSSTATTAGA QEHDAVEILQ ARPAPKARSA TLSSNMLPTI TGQAGARELE VGAPLTSELA
HGMQSPLERL HRGLEGRKEG EEWRRGDSLL GVGAKGEESD EEQGQMQRSE SAMAVREKAI
LERKRSKNGG KGGRRRSSST SDAPLAETTS APMSTLSAMP EFGFENRLND ALPGTSAGFG
DNVQSSLDDI FNSRNRTYRV HERKAVVYAA DVSAGVKSAG DVDPGRAWRK KRPSNMHEVN
RSLSVMSISS TSSSKKSRAL TGQLFVQLRE ASIEGMPFPR ERTSVTFSLD NGRQRVEAGI
RVLDSKVVIR NEFDLVCSEG LAFTIDLHVP PKPAPPPPML TPAPPASPTK KSGFRSVFSS
PKKKVATPPV RAAAPQPLPD PFYDFVDRDG KIASAHFVFA EEASKCKLRK HRFNVPFTNV
AARKACKGAM SIDMLYVPAT PSIPRDSLPK SMDEALAGME AAERASKIIH EGVLTQLGGD
CSIWRRRNCK LRGNRLVPYN EVTKMSHVEI DLSLVTSVDD LNAPSPASTP GSRATTYDAD
AELGAMDHSF RLVFKDASSI DFFADAAETK EQWLEILRKE VAIATVNTKA PPSWALTMRK
LVAAGHPLAA WGASREGESA AERATREAEE KRVSDQIDRR LADEEKEKRK LARAGNQLEV
LIVGATGAGK STFVKQLRLT YDSKGLDAER EATRLVIILS ICSTVRTLIS LLEDDAADPS
SSPSSSRPLS PNGQPRSAEE AIAVRRLRLA PLLGLEAPIR EMLGAVSSGP SANSFAQQAV
LPVEGQLEYR DGEGSGPHSA SPELRRRDQV RSRVGSPAGS EHDEPMLPQG FRERLGHLAF
GNGKESRRAK AQQGSNASVR NSIIDSSLNW TEDGKFNAHS EDPIHLVSAL RTEIESLWTE
AVNQGLVAGE GPLQGKLGGW EPSDSSRYFL DSLPRIASPT WLPSDADVLN VRVRTCGIET
HFLQVTPTQS YRISDPAGAR GIKHAWAPYF DGAAALIFVF DASAFNVCSP SDPTANRFAD
ALDLFEDVAT NSILKNVVII AFLNKVDILR KKIKSGLYPL ERYLPTYQGG TRSQEVLSHM
QALVENRHPK ERKRPLYIFA TQANDTKSIQ MVVAAVNDIL MRSTLAASGL L
//
