ID   A0A1Y2GHY0_9FUNG        Unreviewed;       760 AA.
AC   A0A1Y2GHY0;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   28-JUN-2023, entry version 18.
DE   RecName: Full=Sphingomyelin synthase-like domain-containing protein {ECO:0000259|Pfam:PF14360};
GN   ORFNames=BCR41DRAFT_387827 {ECO:0000313|EMBL:ORZ11390.1};
OS   Lobosporangium transversale.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mortierellomycotina;
OC   Mortierellomycetes; Mortierellales; Mortierellaceae; Lobosporangium.
OX   NCBI_TaxID=64571 {ECO:0000313|EMBL:ORZ11390.1, ECO:0000313|Proteomes:UP000193648};
RN   [1] {ECO:0000313|EMBL:ORZ11390.1, ECO:0000313|Proteomes:UP000193648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 3116 {ECO:0000313|EMBL:ORZ11390.1,
RC   ECO:0000313|Proteomes:UP000193648};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the sphingomyelin synthase family.
CC       {ECO:0000256|ARBA:ARBA00005441}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORZ11390.1}.
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DR   EMBL; MCFF01000028; ORZ11390.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2GHY0; -.
DR   STRING; 64571.A0A1Y2GHY0; -.
DR   InParanoid; A0A1Y2GHY0; -.
DR   OrthoDB; 2880501at2759; -.
DR   Proteomes; UP000193648; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd01610; PAP2_like; 1.
DR   InterPro; IPR045221; Sphingomyelin_synth-like.
DR   InterPro; IPR025749; Sphingomyelin_synth-like_dom.
DR   PANTHER; PTHR21290:SF25; SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1; 1.
DR   PANTHER; PTHR21290; SPHINGOMYELIN SYNTHETASE; 1.
DR   Pfam; PF14360; PAP2_C; 1.
PE   3: Inferred from homology;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193648};
KW   Sphingolipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        155..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        319..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        348..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        621..641
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          292..360
FT                   /note="Sphingomyelin synthase-like"
FT                   /evidence="ECO:0000259|Pfam:PF14360"
FT   REGION          413..437
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          668..719
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        668..715
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   760 AA;  85986 MW;  E7038E496E42CAC3 CRC64;
     MDHHIQIEHF GDESDRSQSQ FQFPYTSYYD TNNSIELDLE AVERDRFDRL SNSSTLVGGT
     SPLRHPYSPE FNSNNSYFID DFKSNGNTIA TIATTTTTDT DINATTTITS ASVAAPAITV
     YKARRRKYDG TDENEKKKTN GSLWYRFFYS EGGRLTCAVV YFVVICIGMA FCNQLSDHRW
     VNTGYTDVLL RDRGFDVIEA QADIQPANTF VMTSVVFTVL GIGLICPNWT MRGIVLRRIL
     WVIGTLSAFR ALTLSVTTLP TPKEECRPSL KTGFWDMFIV ALQMIPGTVE ACTDDIFSGH
     TVFMVSCAIQ WRLYCRNKWV TYFSYLYISI GLYYVIATRL HYTVDVVLAI FITFAGWSVY
     ICMIDVVMEE EYFGIKSHHE KYAVFNTAAA EYEFVTQEQD RAIDEEDEEV KVTISSTTTS
     TTSTLTPNPT KSQTISSRRK QLEYHMNRLR GPRIGYGRGE YDRVAFVPMQ FNLWLKNVVR
     WCDGLDLRMN PYIAENPSTG EQEEEEGLSS LSSSSRWNEL VVRYRAELAS ITGARCDCKK
     TDGELENNLN GYNELGRHRE MVQVYRSGSG LESVHIHNYM EERGQQQHGR WRSMALRTSP
     RSRSPDLKAA KAKKMERNRK LFVLKIALVI FVNVILLIKV IETVQNNSSA AASSSQWPTE
     MKTYPGGTIY NNNNSYPNSP TSHATAPSGP SSLLTPSTQD EEHQVQASPE ESEVGNDSNK
     AGAIAVALDD YKVIKEAVHH RGIQRRNSVG KRNLKQAEAI
//