ID A0A1Y2GSS8_9FUNG Unreviewed; 1121 AA.
AC A0A1Y2GSS8;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=PH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BCR41DRAFT_321096 {ECO:0000313|EMBL:ORZ20038.1};
OS Lobosporangium transversale.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mortierellomycotina;
OC Mortierellomycetes; Mortierellales; Mortierellaceae; Lobosporangium.
OX NCBI_TaxID=64571 {ECO:0000313|EMBL:ORZ20038.1, ECO:0000313|Proteomes:UP000193648};
RN [1] {ECO:0000313|EMBL:ORZ20038.1, ECO:0000313|Proteomes:UP000193648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3116 {ECO:0000313|EMBL:ORZ20038.1,
RC ECO:0000313|Proteomes:UP000193648};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORZ20038.1}.
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DR EMBL; MCFF01000013; ORZ20038.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2GSS8; -.
DR STRING; 64571.A0A1Y2GSS8; -.
DR InParanoid; A0A1Y2GSS8; -.
DR OrthoDB; 1367385at2759; -.
DR Proteomes; UP000193648; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd00174; SH3; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12844; CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS; 1.
DR PANTHER; PTHR12844:SF42; CONNECTOR ENHANCER OF KSR PROTEIN CNK; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00033; CH; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00454; SAM; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000193648};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..63
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 218..281
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 581..677
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 899..1004
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 51..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 700..721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 745..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 815..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1003..1093
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..355
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..767
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..782
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..867
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1052
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1075..1093
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1121 AA; 124301 MW; D99F348FB846AF29 CRC64;
MPETVWAIHN FEAEAEDEIS FQIGEPIIVL HRDELYQDGW WEGTNVRGET GLFPQNYTTQ
NPPEKPLPEA PSSDSNAYGS NTNSGVGSND YNGNGNSRNN NQNYASNITN NSSSMGHTTD
NLNNNHNNSN IRTHESQTNS NVRMLAQQSQ SNYNNTPSNG NNMYIQQNPV IASPSVDSTR
GGSLSGGSIN GAPTSKIIAQ NVEESLSDPQ LAGHPSTWSI DQVAHWLRCC GFGTVVSSFI
DNEISGAILL ELNLNNLKEL DITSFGKRFN IINAITSLKQ LTKSNLDSKN SYGGLSNMSS
MYSVGSPGGP NIPPRMTSAP INVPANGVNL PEPRASYDSR GDYLRDSRHK DLSDPRNAPL
PPGPSHNARL YQQIHAQNLA SSSQQPLQTL PQQQQFSDYD IQAGQPQNRS AANLARSDTL
GSVMSGASIG DYGSPTLVDA PSLNGQRQSA TSAFSSNPNL HRSNNPWDRH ASRAPQPQMP
SPVASQPRGA LSTDFDNMGY GQQQSPQPQL PMDHYPRPME VSRNAPGSPE VLRPDPYSNS
MMYEQPTPKP RKFHNPDTTN RPQNGKADPS DKVVPLELIG RPDYAGWLKK RGDTYRTWKS
RWFMLKGVTL YYMNSPKDSA SKDYINLVGY KIIQDENIYA GKYCFKAVHE DLRNFYFYTD
SESDMKGWLK ALMKVTIGRD PTAPVISSSN IPTIPLHVAR KLAPRPPSPS RRVNRNLGAN
GQPIHSQQLQ KLQYDQGFQQ QKQLLQQQMQ QLQQSSQPQP RSSHQQQQLL DYDDHDSDGE
GYHPNDYSNN HPGNIPQKNG DEKRIAEHPE SPVLQSLSVD QQRHSFVHSD QRDGDDDPWR
DEDGEGFGHQ QKQQQQQQQQ QQQELKYLRP DSELDSFRQP KDVSQPKIQE QEPLPINTRW
TQEQYVEWIN RHLPSTVEPV SDMTQSLRSG VVLVRLIEQL SGETVDKRVP NATYTLQMLE
NLLTAFKFMD RVGVSTDGYT VKDVFNGNEE KIAFMFEAIR ARFPENTPSG PNPTGTNSNA
SASSVSTLHQ QQQQLSASSS LSTLNASVAP ASSLPPLPNG PSKGSPVPKM NGRASPAVMN
NNSGRSPLIG NANTPRMQIQ HIGDESEYEA LYDEAARSTI S
//
