ID A0A1Y2H8Q1_9FUNG Unreviewed; 1002 AA.
AC A0A1Y2H8Q1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Muts domain V-domain-containing protein {ECO:0000313|EMBL:ORZ30073.1};
GN ORFNames=BCR44DRAFT_1446409 {ECO:0000313|EMBL:ORZ30073.1};
OS Catenaria anguillulae PL171.
OC Eukaryota; Fungi; Fungi incertae sedis; Blastocladiomycota;
OC Blastocladiomycetes; Blastocladiales; Catenariaceae; Catenaria.
OX NCBI_TaxID=765915 {ECO:0000313|EMBL:ORZ30073.1, ECO:0000313|Proteomes:UP000193411};
RN [1] {ECO:0000313|EMBL:ORZ30073.1, ECO:0000313|Proteomes:UP000193411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PL171 {ECO:0000313|EMBL:ORZ30073.1,
RC ECO:0000313|Proteomes:UP000193411};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORZ30073.1}.
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DR EMBL; MCFL01000105; ORZ30073.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2H8Q1; -.
DR STRING; 765915.A0A1Y2H8Q1; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000193411; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF148; DNA MISMATCH REPAIR PROTEIN MSH6; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000193411}.
FT DOMAIN 919..935
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 26..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1002 AA; 108520 MW; 61F46CBB5F8A8612 CRC64;
MSQRTPKASA KALGAATDSK VQSNLFKFFG KKPTPSKAAT STPTSTPAPT SNSQAASTPA
SATPSPAITV SGSAAPAQHK PLDHAARSLL TPSSDATQAP AAESSTATPK ANSSVKSKPA
IKRRRIIMDS DEDQDDLDHD VENHHSTSST STTTPSAPPA TKRARTSATP AVSTARKTPS
AAGSPSPFTA TPSKPPSKRS KSVVTPASKP AATPKPGSNA SDWLLNPRDK EGRFPHEEGY
DKSTLWIPKS AWERFSNFEK QFWEVKGTHW DCVVFFQKGK FFELYATDAD LALQLFDLKV
SDNGRGAMRM AGVPESAFEE WAAKFIARGY RVAKVVQSEN AIAKAIRDKQ ATTKADKIIH
RELTCVLTPG TLAEPHFLTN SPDPIYCTGR LFDVASSRLY LACLETETLG GLDTLLTHTQ
PREIVVQPKL DMTMMRNIRA LAPGADLVQV AVDNPQAGRH LISATWAAEE GVPEVVKRMA
GEFRDVETSE VQDLVASALG RLIMYLQRLK RHELLAASAT VEEWTLQSSK HMVLDGAALA
ALAVIDGDDN KSLFHALDYT VTPTGRRLLR SWLAHPLRHR EDILERQRGV VVLGRDHELR
KVVKGGLKAI SVDLERSLNV QARKSLAVLA NVVRGLQSAI ALLEQVMAES SEMQALVHKA
LKDVALDKTL ELIRAEFEAA IVWTGGASCG VEFNPDTDAE YLQARQEVDV VEDQIEELRA
DTQRHLVPAG KVVPNADKTS STKSVARYQT RELKDLNRKF STYIQVWRAI AHAAATVDVM
YSLAVAAEAN KYTCVPDIVA PESTSDGTSI VQAVDLTHPC FSQHVPNDIS LGSSKGEPHM
LLLSGSNAGG KSTVQRTIAT ASILAQIGSL VPATSFRLVP FDSIHTRIGA RDDLAQGMST
LALELHEMSR IIKHATRSSL VLVDELGRGT STYDGMAIAS ATLFELILRG CCCVFTTHYH
SLVHDLQSEF ASAQAGGIAA KVKCMQMEVE NMGHRKVKFC YK
//
