ID A0A1Y2I1X5_9FUNG Unreviewed; 1310 AA.
AC A0A1Y2I1X5;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=BCR44DRAFT_1411720 {ECO:0000313|EMBL:ORZ39973.1};
OS Catenaria anguillulae PL171.
OC Eukaryota; Fungi; Fungi incertae sedis; Blastocladiomycota;
OC Blastocladiomycetes; Blastocladiales; Catenariaceae; Catenaria.
OX NCBI_TaxID=765915 {ECO:0000313|EMBL:ORZ39973.1, ECO:0000313|Proteomes:UP000193411};
RN [1] {ECO:0000313|EMBL:ORZ39973.1, ECO:0000313|Proteomes:UP000193411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PL171 {ECO:0000313|EMBL:ORZ39973.1,
RC ECO:0000313|Proteomes:UP000193411};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORZ39973.1}.
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DR EMBL; MCFL01000004; ORZ39973.1; -; Genomic_DNA.
DR STRING; 765915.A0A1Y2I1X5; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000193411; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47835; HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG; 1.
DR PANTHER; PTHR47835:SF2; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ORZ39973.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000193411}.
FT DOMAIN 512..691
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 721..935
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 45..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..325
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..383
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1310 AA; 142754 MW; 37A43D1412AE8FF3 CRC64;
MYSRMGRQLV ETSVRVRHAS ETVTVRHCHG FPDRLTSSRS FHFASHRAGP VQHQPPESDR
TVASSPHGPP PAASHVFRIL EPSLGLPFIV LGWRQPNPRA GHYGHSLHRP RVNGIDHVQD
VSPPPPPPSS SSMAALLSAS GTRHRGGIGI ESAATRVDRL VVHPTAPPLP YSHNGTATGH
TSSSTHRITS RFWTNPTSST PAFPATPSTT TTSSFFSARP SNVRTPSVFP ATPHRTQPQV
SLPMPAQTPR VSSTISSPPV DLSFVPATPA SSALRPFSTR GSAVIGAHHP LQHSAFASAS
RAVSVSPRPS KHSHNPPPQP PPSASFERPY GDQVGPHHSP CPSPRPTLPP PANDVIADFR
ARLNRQPNAA QGARQSHQSA FSWDTHRLPA AVSAPQRTSR YGHDEPEEET NYEEPQAVGS
NVFAALSGHG TRTHNPPFDV EHVARPAHCG PPPPPPAMGP PMHQAQGMVP ATVLAMRNGG
RLPVKPVSDL PPRFRGMFSF PYFNYIQTQC YDDLMHSDTN LVTSSPTGSG KTALLDLALI
RLWSTHPTPR AVYLATTKAL CSERAADWTR RLQPLGITVA ELTGDTSLFD ARGAQSAQLL
VITSEKYDAV TRRWRESART RQFVAQVGLV LLDEVHLLAS SRGSTLEALV ARMKVVSAEL
NTRIRYIALS ATFPNIEDVG KWLGGGAKVF TFGDEYRPVR LERLVLGYST AHRSSWQFDK
VLDAHLPNVI REHAAGKPAL VFCATRKATE ATAKLLVADG GGLVPGTNGH LFVRTSQHAR
ALVEAAQRVR NQAARELVVH GVAFHHAGVE MADRQLIEQL FLAGQLLVLC TTSTLAVGVN
LPAYLVVLKG TQSWTGGEMK EYAPMDVLQM LGRAGRPQFE TSGKAIIMTT SNKVDEYESL
VAGRTVVESS LHSNLIEHLN AEIAQGTITN EQLAVQWLES TFLYVRLRAA PFYYANVVHG
SDNLRQLVAS TLQVLRAAEM VRESQLECTE YGKLMSRYCL SLQTMQALMA GGPSIPQQLY
AMALASEFSG TYVKAGDKTM LADLNKMQGI KFRLPDKYKY KSTADKVYLV VQAVLGSVQL
QGKDLDRLRV FVSCEQGNIW SALGRIAAAA VELHVARRDT VPYAADRIRH AILLLQSVRT
KIWFDSTRLL RQVDKLGPVL TSTLAEAGIT TFAELASAPA WRLEQLCRRN PPFGSGLVTA
ANQFPHLGVL GRLLQSTLLL SVNISNAATC KKGPHGSSAS WVHVLVHDEV GKLFFMTGSH
STTWPRPSTR PESRCHQVFI VCLRRCWPRI MLGWMAFASG SQDETSVSHA
//
