ID A0A1Y2KB09_9PROT Unreviewed; 1048 AA.
AC A0A1Y2KB09;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Putative Heparinase II/III family protein {ECO:0000313|EMBL:OSM07114.1};
GN ORFNames=MAIT1_03974 {ECO:0000313|EMBL:OSM07114.1};
OS Magnetofaba australis IT-1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Magnetococcales;
OC Magnetococcaceae; Magnetofaba.
OX NCBI_TaxID=1434232 {ECO:0000313|EMBL:OSM07114.1, ECO:0000313|Proteomes:UP000194003};
RN [1] {ECO:0000313|EMBL:OSM07114.1, ECO:0000313|Proteomes:UP000194003}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IT-1 {ECO:0000313|EMBL:OSM07114.1,
RC ECO:0000313|Proteomes:UP000194003};
RX PubMed=27801294; DOI=10.1186/s12864-016-3064-9;
RA Araujo A.C., Morillo V., Cypriano J., Teixeira L.C., Leao P., Lyra S.,
RA Almeida L.G., Bazylinski D.A., Vasconcellos A.T., Abreu F., Lins U.;
RT "Combined genomic and structural analyses of a cultured magnetotactic
RT bacterium reveals its niche adaptation to a dynamic environment.";
RL BMC Genomics 17:726-726(2016).
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSM07114.1}.
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DR EMBL; LVJN01000015; OSM07114.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2KB09; -.
DR STRING; 1434232.MAIT1_03974; -.
DR Proteomes; UP000194003; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd03801; GT4_PimA-like; 1.
DR Gene3D; 2.70.98.70; -; 1.
DR Gene3D; 1.50.10.100; Chondroitin AC/alginate lyase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR008929; Chondroitin_lyas.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR012480; Hepar_II_III.
DR InterPro; IPR031680; Hepar_II_III_N.
DR PANTHER; PTHR39210; HEPARIN-SULFATE LYASE; 1.
DR PANTHER; PTHR39210:SF1; HEPARIN-SULFATE LYASE; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR Pfam; PF07940; Hepar_II_III; 1.
DR Pfam; PF16889; Hepar_II_III_N; 1.
DR SUPFAM; SSF48230; Chondroitin AC/alginate lyase; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Periplasm {ECO:0000256|ARBA:ARBA00022764};
KW Reference proteome {ECO:0000313|Proteomes:UP000194003};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 181..342
FT /note="Glycosyl transferase family 1"
FT /evidence="ECO:0000259|Pfam:PF00534"
FT DOMAIN 501..720
FT /note="Heparin-sulfate lyase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16889"
FT REGION 455..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1048 AA; 115482 MW; 541F19696E5BE2A1 CRC64;
MLILAPAGGN PHVLVGKPGG VGLYTRNLLR RMEPGVEMVH FVTGKRPGDP GWLWPLRLLG
DAIRLKWTLF FQRFDIIHLN PSLNPKSTLR DALFLATIIG MRWWRRPRVL VFFRGWEWST
ADAIQRSGWK RRGFRFLFGA ADHILVLAST FRQRLEQLGF DGARIELAAT MFDGDLIPTE
PAPPHDEIGV LFLSSMNRNK GVTELLEGFA QVAAELPQLR LTLAGEGSAR AGAQTWVAAQ
GLGDVVSLPG YVSGAAKGAL LQQADIFALP SRHGEGCPNA LLEAMGAGCA VIASRAGGIP
DVITSDEHGE LLPEVSAAAV ADALRKLAGD SERLARCQAH NRETAWARYE SRQAAREMAQ
RYRRMLIAPA SATGGGKLRW YAARLRAMSL GEIAYRAQRA VQKRLERRGW LTLPQPPAPT
IVPATTWLKI PENEDPTVYT AAADAILAGT IPLFDEPTPG LGQPPNFNAD PATGDEPFAA
GGADRKHSHS NPEKSRAKRR IWELNRHLHW VTLAQAWRVS GDKRYRDALL EQMRAWLDQC
PYRTGPNWTS PLEMGVRLIN WALVWQILGG PHADCFQGGL GQELRDRLLA AVMQQAHYIQ
RHLSRHTSAN NHLIGELAGL YVASRAWPYW PALARWGEDA KWELNEQIHL QVHVDGVGCE
QTLDYQGFIA EFFLIAALVG ARTDDAFNAA YSSRMERMLA FLHAMLDAGG HLPQIGDADN
GRAFCLNPAR DPAPQALLRL GAVCFARADF QAQAGALDVQ SRWLMGAHGR DRWAALARTP
KAPRKQAFPQ GGYYILGQEF ETADEVHACV DCGPLGYLAI AAHGHADALA LTLSLGGVPI
LVDPGTYDYH AGKQWRSHFR STAAHNTVSI DGADQSTQSG PFLWLNHAQS ACEAWEPEAA
DDLFVGVCHG YERLPDPLTH RREARLFKAE SRLTTQDELI CRAPHEATRT WQFAAGAAVT
QSGPQEVEAV VGPWRVTLRA DEADARLEII TGREEPPAGW VSDRYGRKQA APCVRFINTV
AAATTLKCEI RWRRDADTEE YQGSKSHA
//
