ID   A0A1Y2LLX2_EPING        Unreviewed;       423 AA.
AC   A0A1Y2LLX2;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00497, ECO:0000259|PROSITE:PS00498};
GN   ORFNames=B5807_09174 {ECO:0000313|EMBL:OSS44973.1};
OS   Epicoccum nigrum (Soil fungus) (Epicoccum purpurascens).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Didymellaceae; Epicoccum.
OX   NCBI_TaxID=105696 {ECO:0000313|EMBL:OSS44973.1, ECO:0000313|Proteomes:UP000193240};
RN   [1] {ECO:0000313|EMBL:OSS44973.1, ECO:0000313|Proteomes:UP000193240}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ICMP 19927 {ECO:0000313|EMBL:OSS44973.1,
RC   ECO:0000313|Proteomes:UP000193240};
RA   Fokin M., Fleetwood D., Weir B.S., Villas-Boas S.G.;
RT   "Genome sequence of the saprophytic ascomycete Epicoccum nigrum ICMP 19927
RT   strain isolated from New Zealand.";
RL   Genome Announc. 0:0-0(2017).
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DR   EMBL; KZ107855; OSS44973.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2LLX2; -.
DR   STRING; 105696.A0A1Y2LLX2; -.
DR   InParanoid; A0A1Y2LLX2; -.
DR   OMA; GGPFCYT; -.
DR   OrthoDB; 4070889at2759; -.
DR   Proteomes; UP000193240; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF125; TYROSINASE COPPER-BINDING DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193240};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..423
FT                   /note="Tyrosinase copper-binding domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5013186524"
FT   DOMAIN          138..155
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          346..357
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   423 AA;  46564 MW;  AEA12D9DE8F840F2 CRC64;
     MRTTTVLAAI LPVALSSATP VTSEISPALA LDKRQDVALQ SLGGKILQAD VYAGVAGLNQ
     QIYQATQQSS QWKTCNPLNI IVRREWSAFS TAEKKDYISA VKCLAKLPPK FPKSLCPGCQ
     NRYDDFVATH IRQTFSIHNT GNFLPWHRYF TYAYEKTLRD ECGYKGYQPY YNWPKWSDDP
     AKSPLLDGSE TSLGGNGVLG CTNQTTYGIP TNASPLINIP HGSGGGCVAS GPMKDWPVNL
     GPVFTDLTCT PNNPIFDYTD PTTAGQVGLG YNPRCLKRDI SKWTSSQWSN DEMVVKLLDS
     KDMKTFWYDM QGGENTFSNN FMGVHTAGHF TVGADPGSDF LTSPGDPYFY AHHAQIDRVW
     WTWQNLNPAE RTKAIYGTTV LADPTAPNTT LSDSMTLEYA FAGNITVGDA MSTMGGPFCY
     TYI
//