ID A0A1Y2LRC9_EPING Unreviewed; 703 AA.
AC A0A1Y2LRC9;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Carotenoid oxygenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=B5807_08088 {ECO:0000313|EMBL:OSS46139.1};
OS Epicoccum nigrum (Soil fungus) (Epicoccum purpurascens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Didymellaceae; Epicoccum.
OX NCBI_TaxID=105696 {ECO:0000313|EMBL:OSS46139.1, ECO:0000313|Proteomes:UP000193240};
RN [1] {ECO:0000313|EMBL:OSS46139.1, ECO:0000313|Proteomes:UP000193240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ICMP 19927 {ECO:0000313|EMBL:OSS46139.1,
RC ECO:0000313|Proteomes:UP000193240};
RA Fokin M., Fleetwood D., Weir B.S., Villas-Boas S.G.;
RT "Genome sequence of the saprophytic ascomycete Epicoccum nigrum ICMP 19927
RT strain isolated from New Zealand.";
RL Genome Announc. 0:0-0(2017).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
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DR EMBL; KZ107852; OSS46139.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2LRC9; -.
DR STRING; 105696.A0A1Y2LRC9; -.
DR InParanoid; A0A1Y2LRC9; -.
DR OMA; TRLHRWR; -.
DR OrthoDB; 318119at2759; -.
DR Proteomes; UP000193240; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF89; CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000193240}.
FT BINDING 232
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 293
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 356
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 659
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 703 AA; 77480 MW; 3726B0F2261453FD CRC64;
MSNNGQSKRN AKKHPYLAGN FAPVTKTWTP TSVSWTGDLP KELNGGMYVR NGGNPMANSD
LGRDAHWFDG DGMLSGVWFA RSDNSANGLD VQFVNQFILT DVFLSQVESP AICTPILPSI
ATLTNPASCF FWIIWRIIRT VFIVLLSHLP GSGIAIKRIS VANTSVLYHD GRALATCESG
PPIRLTLPEL ETVGWFDGNA VEGEPKARDK KDEPTLGGTG PLSWMREWST GHPKVDNATG
ELVIFHCSFA PPYVQYSIVP STEANLADHH SSETAVRITN AAVPGCTGGK LMHDFGVSKH
STVILDLPLS LSPLNLAKNS PVVAYEPWKP SRFGVFPRQH PEAVRWFETD GCCIFHTANT
WDEFDADGNV AAVSLLACRL TSASVVFSAG NIVPPPHPNH KDVRSEKPMS FFAKYDEESE
KQDPEKIDET SPLISHKDMV PNPFGASSHL PISDDDEEQC RLYYYRFSLD SATENVITHQ
FALAAIPVEF PTVSPLTAMD SARYIYACST SNESFGAALG KASKIDILVR FDVKALLEKA
QSEPPDAITG CVDNRSLAQI MASTDPNDPI KVFQFPPNVY GQEATFLPRS RRGSATNKNT
AFDEDDGYLV FYTFDERQLD EYGECTDDAK SELWVLDAQS MTKVQCKIQL PTRIPYGLHG
NWFTEEQIAR QKGVDKVRTL PPGARAADTQ WSRIKRSIHG RLG
//
