ID A0A1Y2LT24_EPING Unreviewed; 616 AA.
AC A0A1Y2LT24;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=histone acetyltransferase {ECO:0000256|ARBA:ARBA00013184};
DE EC=2.3.1.48 {ECO:0000256|ARBA:ARBA00013184};
GN ORFNames=B5807_08801 {ECO:0000313|EMBL:OSS46732.1};
OS Epicoccum nigrum (Soil fungus) (Epicoccum purpurascens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Didymellaceae; Epicoccum.
OX NCBI_TaxID=105696 {ECO:0000313|EMBL:OSS46732.1, ECO:0000313|Proteomes:UP000193240};
RN [1] {ECO:0000313|EMBL:OSS46732.1, ECO:0000313|Proteomes:UP000193240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ICMP 19927 {ECO:0000313|EMBL:OSS46732.1,
RC ECO:0000313|Proteomes:UP000193240};
RA Fokin M., Fleetwood D., Weir B.S., Villas-Boas S.G.;
RT "Genome sequence of the saprophytic ascomycete Epicoccum nigrum ICMP 19927
RT strain isolated from New Zealand.";
RL Genome Announc. 0:0-0(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-
CC lysyl-[histone]; Xref=Rhea:RHEA:21992, Rhea:RHEA-COMP:9845,
CC Rhea:RHEA-COMP:11338, ChEBI:CHEBI:15378, ChEBI:CHEBI:29969,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:61930; EC=2.3.1.48;
CC Evidence={ECO:0000256|ARBA:ARBA00024456};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:21993;
CC Evidence={ECO:0000256|ARBA:ARBA00024456};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KZ107850; OSS46732.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2LT24; -.
DR STRING; 105696.A0A1Y2LT24; -.
DR InParanoid; A0A1Y2LT24; -.
DR OMA; DQLWVGQ; -.
DR OrthoDB; 2787984at2759; -.
DR Proteomes; UP000193240; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0010484; F:histone H3 acetyltransferase activity; IEA:InterPro.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR GO; GO:0140889; P:DNA replication-dependent chromatin disassembly; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR013178; Histone_AcTrfase_Rtt109/CBP.
DR InterPro; IPR016849; Rtt109.
DR PANTHER; PTHR31571; ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6; 1.
DR PANTHER; PTHR31571:SF2; HISTONE ACETYLTRANSFERASE RTT109; 1.
DR Pfam; PF08214; HAT_KAT11; 1.
DR SMART; SM01250; KAT11; 1.
DR PROSITE; PS51728; RTT109_HAT; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000193240};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 365..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..403
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..460
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 66972 MW; 201C67342102043D CRC64;
MADIPKRKRG SRSLNDLLAE QLPKDVPFTF YHYSTPPTKS PALFSAPPHA KSERTYCESH
FLSATITPKD VHVHVGGSQL PEELLILAIE VLVYSTRNLT TLFVSKADST GYLSELQLSR
SQSSSPLKAI CGTFVSWLAR ERQREGKKLV ISLFARAQDQ YLFPASIDNK NKHVLDDRGL
VKWWCKVLDP IIWEYQAEED RKPFEERLVD GASNGNGTGT GTGTAALHNA NATTAKGYLV
IPGYETYDTL RYVPPPPTPN TPRRWAASHP LLQIAPHPAA PPRCLVPHFP DDPKARFLDE
LDEELPDRGE GVIADGGTPS RSNGMWKSVK TLDQFWEFMA FRQECSSGRI VGFIWVVLSP
PIPSIPEEEA GEDDNAPLAS QRSQLSQPSA YESQASQLSP KKKSRNASAR RTKPDKRPER
RSGPIPLILP RIKSRSSSGL STTSNTSNTT APTPNTPEST PYYICPASSR GTLCLSAKNY
ARAHELLTQM SFATRAAAAR STAQFKKEVA VLGGVAGREW GKVVVGRREG VEREKEGESV
QPVAVVMGVR RKRKDGDAAS ASASAAVEAG TQEGAPVTLD AGLVRKKPKV ASAPADGAVG
GVQVLGAGLV RRKPKA
//
