ID A0A1Y2MF83_EPING Unreviewed; 529 AA.
AC A0A1Y2MF83;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 28-JUN-2023, entry version 17.
DE RecName: Full=Pre-mRNA-splicing factor {ECO:0000256|RuleBase:RU369096};
GN ORFNames=B5807_01802 {ECO:0000313|EMBL:OSS54137.1};
OS Epicoccum nigrum (Soil fungus) (Epicoccum purpurascens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Didymellaceae; Epicoccum.
OX NCBI_TaxID=105696 {ECO:0000313|EMBL:OSS54137.1, ECO:0000313|Proteomes:UP000193240};
RN [1] {ECO:0000313|EMBL:OSS54137.1, ECO:0000313|Proteomes:UP000193240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ICMP 19927 {ECO:0000313|EMBL:OSS54137.1,
RC ECO:0000313|Proteomes:UP000193240};
RA Fokin M., Fleetwood D., Weir B.S., Villas-Boas S.G.;
RT "Genome sequence of the saprophytic ascomycete Epicoccum nigrum ICMP 19927
RT strain isolated from New Zealand.";
RL Genome Announc. 0:0-0(2017).
CC -!- FUNCTION: Involved in spliceosome maturation and the first step of pre-
CC mRNA splicing. {ECO:0000256|RuleBase:RU369096}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU369096}.
CC -!- SIMILARITY: Belongs to the SPP2 family. {ECO:0000256|ARBA:ARBA00008576,
CC ECO:0000256|RuleBase:RU369096}.
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DR EMBL; KZ107838; OSS54137.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2MF83; -.
DR STRING; 105696.A0A1Y2MF83; -.
DR InParanoid; A0A1Y2MF83; -.
DR OMA; AWGKSAM; -.
DR OrthoDB; 55448at2759; -.
DR Proteomes; UP000193240; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-UniRule.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:UniProtKB-UniRule.
DR InterPro; IPR045166; Spp2-like.
DR InterPro; IPR026822; Spp2/MOS2_G-patch.
DR PANTHER; PTHR15818; G PATCH AND KOW-CONTAINING; 1.
DR PANTHER; PTHR15818:SF2; G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN; 1.
DR Pfam; PF12656; G-patch_2; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|RuleBase:RU369096};
KW mRNA splicing {ECO:0000256|RuleBase:RU369096};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU369096};
KW Reference proteome {ECO:0000313|Proteomes:UP000193240};
KW Spliceosome {ECO:0000256|RuleBase:RU369096}.
FT DOMAIN 256..314
FT /note="Spp2/MOS2 G-patch"
FT /evidence="ECO:0000259|Pfam:PF12656"
FT REGION 88..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 124..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..336
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..529
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 529 AA; 60122 MW; F18140072030B21D CRC64;
MEPNFGPCQA RCMSLREMLE QRPTHTSPQP TTGHILHAKH CLCPRKINLA LVSNNSKHPQ
ISTMAAGGFK MSLGGLKAKP GLKAVASKSA AKPKKALLGD EEPEDTNTAQ EIAGFDAASG
GAISANAPAE KKGPLVIPSL PNRNWREEAR RKQLERAPHA QQAQNGDVVM EEPEKEVVYG
LSVPTKPADA LENGTAEEET SQAMDVDAKD DGLTDAQRLD KQALESLLTG KATDTARVVP
AITDEEALQN DLAEAPDEPT IDAYEATPIE GFGLAMLRGM GWKDSDGDNR KGANKPPAEV
KRRPALLGIG AKEDAAKDVE LGEFNSKARP KKGQKGAKDA PQGYNPVSLR NKKTGELITE
EELKRKMEAQ ELVGEEGVGR RDDRGGRDDR SGRDSGRDER SGRDDKSERR RDRDRDRDRD
RDSDRRDDRD RDRRSRDDEY DSERRREKKR DRSRSPRDDR KRRERYRSRS RSRDGKDRRD
RRDRDRNRDR ERSQDQDRDD EERRRRRRRE REREREHDTG RDERRRRDR
//
