ID A0A1Y2MQ99_PSEAH Unreviewed; 548 AA.
AC A0A1Y2MQ99;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Nitric oxide synthase oxygenase {ECO:0000313|EMBL:OSY37159.1};
DE EC=1.14.13.165 {ECO:0000313|EMBL:OSY37159.1};
GN Name=nos {ECO:0000313|EMBL:OSY37159.1};
GN ORFNames=BG845_04853 {ECO:0000313|EMBL:OSY37159.1};
OS Pseudonocardia autotrophica (Amycolata autotrophica) (Nocardia
OS autotrophica).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=2074 {ECO:0000313|EMBL:OSY37159.1, ECO:0000313|Proteomes:UP000194360};
RN [1] {ECO:0000313|EMBL:OSY37159.1, ECO:0000313|Proteomes:UP000194360}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 535 {ECO:0000313|EMBL:OSY37159.1,
RC ECO:0000313|Proteomes:UP000194360};
RA Grumaz C., Vainshtein Y., Kirstahler P., Sohn K.;
RT "Pseudonocardia autotrophica DSM535, a candidate organism with high
RT potential of specific P450 cytochromes.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSY37159.1}.
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DR EMBL; MIGB01000032; OSY37159.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2MQ99; -.
DR STRING; 2074.BG845_04853; -.
DR Proteomes; UP000194360; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004517; F:nitric-oxide synthase activity; IEA:InterPro.
DR GO; GO:0006809; P:nitric oxide biosynthetic process; IEA:InterPro.
DR CDD; cd00575; NOS_oxygenase; 1.
DR Gene3D; 3.90.440.10; Nitric Oxide Synthase;Heme Domain;Chain A domain 2; 1.
DR InterPro; IPR044943; NOS_dom_1.
DR InterPro; IPR044940; NOS_dom_2.
DR InterPro; IPR044944; NOS_dom_3.
DR InterPro; IPR004030; NOS_N.
DR InterPro; IPR036119; NOS_N_sf.
DR PANTHER; PTHR43410; NITRIC OXIDE SYNTHASE OXYGENASE; 1.
DR PANTHER; PTHR43410:SF1; NITRIC OXIDE SYNTHASE OXYGENASE; 1.
DR Pfam; PF02898; NO_synthase; 1.
DR SUPFAM; SSF56512; Nitric oxide (NO) synthase oxygenase domain; 1.
DR PROSITE; PS60001; NOS; 1.
PE 4: Predicted;
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:OSY37159.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000194360}.
FT DOMAIN 248..255
FT /note="Nitric oxide synthase (NOS)"
FT /evidence="ECO:0000259|PROSITE:PS60001"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 166..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 58889 MW; F90AB376408D7369 CRC64;
MTTVEHAASK QPAPAQPTQP VRRPAGFRPS PTPRSTEDPA PSAAAETTVT PAVEPATRAV
TIVPLAGAVE ATTAAATPGS GPEATTVIGP AAPDRSATPA PASAPGPGPA NAAPATADAT
VVVPLRGQGA AVTAVSAPTI ATTSVEPAAG GATVRTPAAA AGCPVTGHGR SGGHPVAPGV
PDERRPKAVD PAAAEEFLRQ VYAETEPELP LRDRLRQVRS EIDRRGVYTH TAHELVFGTR
IAWRNSARCI GRLYWQSLQV RDLRHLHDPA DVAQESVGHL RAATRGGRIR STITVFAPDA
PARPGPRIRN DQLVRYAGHR NPDGSVVGDP SQVEFTDRVV GMGWPRSQPP GRFDVLPLLI
TGADGRSRLF DVPPDAVHEV RLRHPEHPWF ARLGLRWHSV PAISNMPLEI GGVVYPAAPF
NGWYLDTEIG ARNLADPDRY DLLPEIAKRL GLDTRSVRTM WKDRAMVELV RAVTYSFDAD
GVTMADHHTE SERFLRHLEK EEAAGRSCPA DWSWIVPPMS GSQTPVFHRY YDEPDPDLRP
AFLEPHRI
//
