ID A0A1Y2N3M9_PSEAH Unreviewed; 461 AA.
AC A0A1Y2N3M9;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Methane monooxygenase component C {ECO:0000313|EMBL:OSY42082.1};
DE EC=1.14.13.25 {ECO:0000313|EMBL:OSY42082.1};
GN Name=mmoC_2 {ECO:0000313|EMBL:OSY42082.1};
GN ORFNames=BG845_01578 {ECO:0000313|EMBL:OSY42082.1};
OS Pseudonocardia autotrophica (Amycolata autotrophica) (Nocardia
OS autotrophica).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=2074 {ECO:0000313|EMBL:OSY42082.1, ECO:0000313|Proteomes:UP000194360};
RN [1] {ECO:0000313|EMBL:OSY42082.1, ECO:0000313|Proteomes:UP000194360}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 535 {ECO:0000313|EMBL:OSY42082.1,
RC ECO:0000313|Proteomes:UP000194360};
RA Grumaz C., Vainshtein Y., Kirstahler P., Sohn K.;
RT "Pseudonocardia autotrophica DSM535, a candidate organism with high
RT potential of specific P450 cytochromes.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSY42082.1}.
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DR EMBL; MIGB01000006; OSY42082.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2N3M9; -.
DR STRING; 2074.BG845_01578; -.
DR OrthoDB; 9801223at2; -.
DR Proteomes; UP000194360; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0106317; F:methane monooxygenase NADH activity; IEA:UniProtKB-EC.
DR GO; GO:0106318; F:methane monooxygenase NADPH activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR47354; NADH OXIDOREDUCTASE HCR; 1.
DR PANTHER; PTHR47354:SF6; NADH OXIDOREDUCTASE HCR; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR Pfam; PF00175; NAD_binding_1; 1.
DR PRINTS; PR00410; PHEHYDRXLASE.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000313|EMBL:OSY42082.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:OSY42082.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000194360};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 222..322
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 461 AA; 49879 MW; 7D41FF369508DB01 CRC64;
MSRPVPQQAT APVRRDDPAA DAWLAHRRAR LIWGSVLVTA LVGPSVIWML RSGPQPLLHQ
MSVLTGLLAL SALVVVAVLP SRVRGLSGAL GLETLLGLHR KLGMLAGALV ALHLACVVAD
HPERVWLLVP MSAPARGQAA TIGTIAIAVL LLFAVRGVRS GTHEVWRWVH LSLAALVVGA
SSLHVLWLNN LVTDAVMGPV LGTLGLLLVA VLLIRWGARA VGDAGEFRVH VVRPESATVS
TLVLQRRGRH SGPWFRPGQF AWLRLERMSV EEHPFTIASS AVDGGRVEFT VRHTGDFASR
LRELRRGEPV WVDGPYGSFT PDAVPSTGLV LIAGGVGITP MMSMLRTAAD RGDRRPYRLV
VHARDRADLL FRAELAHLRT LLDLQVTEVL RRPSRDWAGA TGPIDTALLS AVLTDLDGAG
GTCRHDYFIC GRPQLVSDVL DTLHSLGVPE DRVHTEQFAQ V
//
