ID A0A1Y2N738_PSEAH Unreviewed; 715 AA.
AC A0A1Y2N738;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Dimethyl sulfoxide reductase DmsA {ECO:0000313|EMBL:OSY42907.1};
DE EC=1.8.5.3 {ECO:0000313|EMBL:OSY42907.1};
GN Name=dmsA_1 {ECO:0000313|EMBL:OSY42907.1};
GN ORFNames=BG845_01149 {ECO:0000313|EMBL:OSY42907.1};
OS Pseudonocardia autotrophica (Amycolata autotrophica) (Nocardia
OS autotrophica).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=2074 {ECO:0000313|EMBL:OSY42907.1, ECO:0000313|Proteomes:UP000194360};
RN [1] {ECO:0000313|EMBL:OSY42907.1, ECO:0000313|Proteomes:UP000194360}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 535 {ECO:0000313|EMBL:OSY42907.1,
RC ECO:0000313|Proteomes:UP000194360};
RA Grumaz C., Vainshtein Y., Kirstahler P., Sohn K.;
RT "Pseudonocardia autotrophica DSM535, a candidate organism with high
RT potential of specific P450 cytochromes.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSY42907.1}.
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DR EMBL; MIGB01000004; OSY42907.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2N738; -.
DR STRING; 2074.BG845_01149; -.
DR OrthoDB; 7376058at2; -.
DR Proteomes; UP000194360; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02766; MopB_3; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR Gene3D; 3.30.2070.10; Formate dehydrogenase/DMSO reductase; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR PANTHER; PTHR43742:SF6; OXIDOREDUCTASE YYAE-RELATED; 1.
DR PANTHER; PTHR43742; TRIMETHYLAMINE-N-OXIDE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00490; MOLYBDOPTERIN_PROK_2; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:OSY42907.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000194360}.
FT DOMAIN 10..68
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 715 AA; 77094 MW; B07158484D3AE00C CRC64;
MTTTDDRPTS TTVRAACPQD CPDTCAMLVT VDGDGKATSV VGDPDHPYTN GGLCVKVNNY
LDRVYDPGRV LFPMRRTGPK GSGRFERITW DDAVTEIATR FKAIADEHGP EAIMPVSYLG
TQGILNGLNV GDPFFAKLGA TVAERTYCDS GSCTAYAMTI GDTAGVDPES LVHSTFILVW
ACNIMSTNLH LWPYIAKAKK NGAKVVVVDP IRTRTAAAAD QHIAIRPGTD GALALAMAHV
IIAEGLTDDD YIANHTVGYD EFAERVSRYT PEWAETETGV PADTIRTLAR EYAGAQPSVI
RIGVAVERHA GGGQTVRALS CLPGLVGAWR KPGGGILQLP LWAFPVNWGA FMHPEMLTPG
TRVINQYRLG AALAGDLPAG PPIKGLMVYN SNPVVTTPDQ DRLIKGLESE DLFTVVSEQF
MTDTAEYADI VLPATTQLEQ DDIMFSWGHL YVTYNHQSIE PLGEAVPNTE MFRRLAAAMG
FDDPVFQRTD EEMIAEAFDW SHPHMEGITV ESLKEQGWQR LNVAPPEAYA PHAEGNFPTP
SGKAEFVSAA AAGGNFVVPL FRQGSNDHQP GQPVDPLPHY IPPRESAAAD PELAARYPLN
LLTPKSHAFL NSSFASHEFH RRVANEHTLI VHPDDAAARG ITEGSPVRVF NDRGEFTVVA
SLQDTVPLGV VVSPMGGWRK NSKAGATLAA VNPTVFGDLG NAPTFSDTLV EVETA
//
