ID   A0A1Y2PDA5_9FLAO        Unreviewed;       965 AA.
AC   A0A1Y2PDA5;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=FAD-binding protein {ECO:0000313|EMBL:OSY88442.1};
GN   ORFNames=WH52_06720 {ECO:0000313|EMBL:OSY88442.1};
OS   Tenacibaculum holothuriorum.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Tenacibaculum.
OX   NCBI_TaxID=1635173 {ECO:0000313|EMBL:OSY88442.1, ECO:0000313|Proteomes:UP000194221};
RN   [1] {ECO:0000313|EMBL:OSY88442.1, ECO:0000313|Proteomes:UP000194221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S2-2 {ECO:0000313|EMBL:OSY88442.1,
RC   ECO:0000313|Proteomes:UP000194221};
RA   Shao Z., Wang L., Li X.;
RT   "Genome sequence of Tenacibaculum sp. S2-2, isolated from intestinal
RT   microbiota of sea cucumber, Apostichopus japonicas.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OSY88442.1}.
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DR   EMBL; LAPZ01000003; OSY88442.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2PDA5; -.
DR   STRING; 1635173.WH52_06720; -.
DR   InParanoid; A0A1Y2PDA5; -.
DR   OrthoDB; 9767256at2; -.
DR   Proteomes; UP000194221; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.70.2190; -; 1.
DR   Gene3D; 3.30.70.2740; -; 1.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR   PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF13534; Fer4_17; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000194221}.
FT   DOMAIN          35..274
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
FT   DOMAIN          617..648
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   965 AA;  108016 MW;  B168E75A4CE6F9BC CRC64;
     MIQKAQLQSL EKSLIGELFF DDLHKNIYAT DASVYRKIPL AVAYPKNKKD IQQLIEFATK
     HQTTLIPRTA GTSLAGQCVG DGIVVDVSKH FTNILAFDEQ AKTITVEPGI IRDDLNRFLK
     PFGLFFGPNT STSNRCMIGG MVGNNSSGST SIRYGVTRDK VLAIDGLLSD GSEVTFEEIS
     SQEFRTKSLQ DNLEGNIYKS IFFELSSKEN QDEIKKEFPK ESIHRRNTGY AVDEFLTSNL
     FGGTEETINP AKFLSGSEGT LVFSTAITIQ LDDLPPTQSI MVCPHFTSVN ESLKATVTAM
     NHKLYACELM DKVILDCTKN NREQAKNRFF LQGDPEAVLM LEVSADTIEE AETLADRLIE
     DLKLNNFGYH YPKVYGEDIA KVHYLRKAGL GLLGNIVGDM KAVACIEDTA VALEDLPEYI
     EEFTQIMDKY QQDAVYYAHA GAGELHLRPI LNLKKQEDVV LFRKITTETA ELVKKYQGSF
     SGEHGDGIVR AEFIPLMIGD RNYQLLRRIK KAFDPHNVFN KGKITDAFPM DQSLRYEIDR
     KEPEIETIQD FSDSEGILKL AEKCNGSGDC RKSPEAGGTL CPSYRATRNE KETTRARANT
     LREVLTNNTA KNKFDSKELK KVLDLCLSCK ACATECPSNV DIASMKAEFL YQYQETNGYS
     FRSKLFANNA KYNKLGSKFP TLTNFFTNTI VAKKVMGVTT ERSVPKLAKQ PLETWLKNYQ
     TKASNKTVYL FNDEFTNYYD AEIGKDAVIV LEKLGYEVKT IAHEESGRSY ISKGFLKEAK
     EIANKNVATF KTLISDQTPL VGIEPSAILT FRDEYLRIAN DKAAAKKLSE HCFTIEEFLA
     SEIEKGNINS DMFTKASKTL KIHGHCHQKA LSSTHASFSI LNIPKNYKVT IMNTGCCGMA
     GSFGYEKEHY KVSMQVGEDT LFPKVRNCSE TTEIVAAGTS CRHQIYDGTK RIAKHPITIL
     KEALS
//