ID A0A1Y2PFP3_9FLAO Unreviewed; 268 AA.
AC A0A1Y2PFP3;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Mechanosensitive ion channel protein {ECO:0000313|EMBL:OSY88831.1};
GN ORFNames=WH52_03960 {ECO:0000313|EMBL:OSY88831.1};
OS Tenacibaculum holothuriorum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Tenacibaculum.
OX NCBI_TaxID=1635173 {ECO:0000313|EMBL:OSY88831.1, ECO:0000313|Proteomes:UP000194221};
RN [1] {ECO:0000313|EMBL:OSY88831.1, ECO:0000313|Proteomes:UP000194221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2-2 {ECO:0000313|EMBL:OSY88831.1,
RC ECO:0000313|Proteomes:UP000194221};
RA Shao Z., Wang L., Li X.;
RT "Genome sequence of Tenacibaculum sp. S2-2, isolated from intestinal
RT microbiota of sea cucumber, Apostichopus japonicas.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSY88831.1}.
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DR EMBL; LAPZ01000002; OSY88831.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2PFP3; -.
DR STRING; 1635173.WH52_03960; -.
DR InParanoid; A0A1Y2PFP3; -.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000194221; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR008910; MSC_TM_helix.
DR InterPro; IPR045275; MscS_archaea/bacteria_type.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30221; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR PANTHER; PTHR30221:SF1; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF05552; MS_channel_1st_1; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000194221};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 102..167
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 174..256
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 268 AA; 29015 MW; 11236C1AF7D0C7AB CRC64;
MEKYWNKIQT LLIDYTPKIL TALAILIVGL FAIKFIVKAT KKVMQKQGVD VTLQRFLGDL
ISWSLKALLF VTVVSKLGVA TTSFAAIIGA AGLAVGLALQ GSLSNFAGGA LIMIFKPFKI
GDLIEAQGIT GVVKEIQIFT THVNTPGNRL AIIPNGALSN GNIINYTAEG KLRVDLTFGV
SYDADIKKTK EILMEVLTSN PKVLQDPAPS VNVSELADSS VNFAVRPWTN TADYWDVYFG
TTENVKLALD KAGIEIPYPH SVEIQKEG
//
