ID A0A1Y2R1D3_9BURK Unreviewed; 2209 AA.
AC A0A1Y2R1D3;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=DNA helicase {ECO:0000313|EMBL:OSZ74539.1};
GN ORFNames=CAP37_03480 {ECO:0000313|EMBL:OSZ74539.1};
OS Hydrogenophaga sp. IBVHS1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Hydrogenophaga.
OX NCBI_TaxID=1985169 {ECO:0000313|EMBL:OSZ74539.1, ECO:0000313|Proteomes:UP000194358};
RN [1] {ECO:0000313|EMBL:OSZ74539.1, ECO:0000313|Proteomes:UP000194358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBVHS1 {ECO:0000313|EMBL:OSZ74539.1,
RC ECO:0000313|Proteomes:UP000194358};
RA Orr R.J.;
RT "Draft genome sequences of novel bacteria, isolated from environmental
RT samples.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSZ74539.1}.
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DR EMBL; NFUU01000001; OSZ74539.1; -; Genomic_DNA.
DR STRING; 1985169.CAP37_03480; -.
DR OrthoDB; 9757917at2; -.
DR Proteomes; UP000194358; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 3.40.960.10; VSR Endonuclease; 1.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR021754; DUF3320.
DR InterPro; IPR025103; DUF4011.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR049468; Restrct_endonuc-II-like_dom.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF11784; DUF3320; 1.
DR Pfam; PF13195; DUF4011; 1.
DR Pfam; PF18741; MTES_1575; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:OSZ74539.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000313|EMBL:OSZ74539.1};
KW Hydrolase {ECO:0000313|EMBL:OSZ74539.1};
KW Nucleotide-binding {ECO:0000313|EMBL:OSZ74539.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000194358}.
FT DOMAIN 695..758
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1555..1598
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1626..1814
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT DOMAIN 1863..1960
FT /note="Restriction endonuclease type II-like"
FT /evidence="ECO:0000259|Pfam:PF18741"
FT DOMAIN 2059..2108
FT /note="DUF3320"
FT /evidence="ECO:0000259|Pfam:PF11784"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1963..1990
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2209 AA; 244039 MW; BA0BF240767349E7 CRC64;
MAQLDWKQTE HENPKPDTTE SVDVVRELRL EAAFSTKLNL ADFQNSVPLL RELQVVSTLT
EESKGLELVL ESIPAFVRAK RWRLDSVGAG QSYRVQELDV QLDGVLLSKL TEAEQATVTL
TLKRADAGPQ DDPVVISRKV ELLPRNQWGG IAHMPDMIAA FVQPNEPAID RLLKKAADVL
RDNGKDASLD GYKGGPKRAW EIASAIWGAV VGMKLDYALP PASFEHSGQK IRSSGQIADS
GLATCLDLAL LFCSALEQAG LNPLLIFTKG HAFAGVWLKH EEFSSSVVDD ITALRKRVKL
KELVLFETTL VAQRPGVPFR FAADNGTSQV SEEQAERFEL AVDVRRARLQ RIKPLASNET
PLHQAKPEDD GPTVVPFDEA PDLPDDIIVE GKPSTLDPKD RLARWQRKLL DLSMRNNLLN
FKAGKKSLKL EAPDPGALED LMSDGKEVRL LQRPDLMDGS DPRNQAIHEA RERENLRRTH
AVDALKRREV FVSLPQEELE TRLVDLYRSA RTTLQEGGAN TLFLALGFLT WTRDEKDEKT
FKAPLVLLPV TLNRKSVRSG FSLTIHEDEP RFNPTLIEML RQDFKLELGI QGGELAQDDA
GVDIAKIWRT VSAAVKDIKG WEVSEDVYLS MFSFAKYLMW VDLVQRTDQL RQNNVVKHLL
DTPRDPFPST SSFPNPKVLD RDFGPEQTFC PLPADSSQLA AVMAAARGKD FVLIGPPGTG
KSQTISNLIA QCLAENKRVL FVSEKIAALD VVYRRLREVK LGEFCLELHS NKARKLDVLA
QLKTAWEAKG DIDPEAWAAE ARRLKRLRDE LNVYVERLHH KHSNGQSIFD AIGVVVAGAD
MPALGLSWSS HSAHGAKDTE KLREVVDRLA VNASAVGPNA LTSGPLKDVG QDDWSPTWQQ
MLIDAARAVV PVAERIQNTA ESFCQAIGLE TGQLTRRRRT ALATLSRALP MASGKDWRFA
FRADAKTISE ALSAGCKLVV EHAQLNAELS PGWTAGVVHD AESGADLLAR RTDLVGSLAR
PWPADAQESI ANGVKLLERL ESLGKTLSVR YSDGIEQVNV YLLHREYAKA QKSVWPMSWA
GKRKVRKILE ALVAGDGEPS VANDLTALVA IRDTRSAIEK HDIGPEASGI WFGLKSRAEV
LTGALKLQAA AAAVKQGLAW TDEGLDALAA GRGGETLAGE VQKLRSIGEL DQRINAFPNL
RSQTGGLWRG LESDVHILRV ATIFARLLEI IRSRGTMEGE LQLVATGACG EMFSRDHQLL
AKRTACERQL SSFDQLGMST HGVWKGLDTD VQDVEKAIRF QGSIAAAISN LALAPSEVPA
VSAVLERLVV DGNGLLDVNG PVAGRGQDYL DAWAKLQPAV DKLAQQGHFS DLAQADFQEI
DIESLVGRCK NLVQSEARLH AWCPWRKVRG EAITLGLSPM VAGLENGAVA PADVMKAFET
NYCRWWLNAV VDSEQVIRTF VSAEHEKRIA DFRALDSKFT ELTRAWVRAS LCSGLPSPED
VTRNSEWGLL RREITKKRAH LPLRELIGGI PTAMVKLTPC LLMSPLSIAQ YLAPDSEQFD
VVVFDEASQI PVWDAIGAIA RGKQVLMVGD PKQLPPTAFF DRAESSLDDE EVEGDMESIL
DECLGANLPT LDLSWHYRSR NESLIAFSNH RYYGGELVTF PSPVTEDKAV SFHYVKGVYE
KGGARINKPE AKAVVADVVA KLKSPGFRAS KHTIGVVTFN SEQQKLIEDL LDEERRKDPS
IEPHFSEAEL EPLFVKNLES VQGDERDIMY FSISYGPDMS GAVSMNFGPM NRDGGERRLN
VAITRARQEL RVFSSLKPDQ MDLSRTQAHG VRDLKHFLEF AERGPKALAE ATRGSLGDFE
SPFEEAVAGA LAAKGWELHA QVGASSFRVD LAVVHPDAPG TYLSGIECDG ATYHRSATAR
DRDKLREQVL RGLGWDILRI WSTDWWVDKN GTLDRIHAKL AALLEVSRKR RAEEAEMAAA
KEAAEAALRK AHATVPAANK HPGEATRSGT ALSEESVEVF DEVYARNAAQ QGSSDLTSSQ
GQFYREVPTE ELEGAAVADR FYEASYESVL IAMIEHVIQT EGPILDSVLA RRISRAHQWQ
RTGGRIQERV EAIARQRFKN SKEDVGTFYW PQALPPGSPV AFRRPPEEQQ RSIDEVCMPE
LQALAQMCHD PVNTDDENLV SMARALGIQR LRAASRVRLE EALRAVNRR
//
