ID A0A1Y2R3W5_9BURK Unreviewed; 596 AA.
AC A0A1Y2R3W5;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Arsenical pump-driving ATPase {ECO:0000256|PIRNR:PIRNR001327};
DE EC=7.3.2.7 {ECO:0000256|PIRNR:PIRNR001327};
GN ORFNames=CAP37_04930 {ECO:0000313|EMBL:OSZ74801.1};
OS Hydrogenophaga sp. IBVHS1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Hydrogenophaga.
OX NCBI_TaxID=1985169 {ECO:0000313|EMBL:OSZ74801.1, ECO:0000313|Proteomes:UP000194358};
RN [1] {ECO:0000313|EMBL:OSZ74801.1, ECO:0000313|Proteomes:UP000194358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBVHS1 {ECO:0000313|EMBL:OSZ74801.1,
RC ECO:0000313|Proteomes:UP000194358};
RA Orr R.J.;
RT "Draft genome sequences of novel bacteria, isolated from environmental
RT samples.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Anion-transporting ATPase. {ECO:0000256|PIRNR:PIRNR001327}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=arsenite(in) + ATP + H2O = ADP + arsenite(out) + H(+) +
CC phosphate; Xref=Rhea:RHEA:11348, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:29242, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.7;
CC Evidence={ECO:0000256|PIRNR:PIRNR001327};
CC -!- SIMILARITY: Belongs to the arsA ATPase family.
CC {ECO:0000256|ARBA:ARBA00011040, ECO:0000256|PIRNR:PIRNR001327}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSZ74801.1}.
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DR EMBL; NFUU01000001; OSZ74801.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2R3W5; -.
DR STRING; 1985169.CAP37_04930; -.
DR OrthoDB; 9780677at2; -.
DR Proteomes; UP000194358; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0015446; F:ATPase-coupled arsenite transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd02035; ArsA; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025723; Anion-transp_ATPase-like_dom.
DR InterPro; IPR027541; Ars_ATPase.
DR InterPro; IPR016300; ATPase_ArsA/GET3.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR04291; arsen_driv_ArsA; 1.
DR NCBIfam; TIGR00345; GET3_arsA_TRC40; 1.
DR PANTHER; PTHR10803; ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE; 1.
DR PANTHER; PTHR10803:SF3; ATPASE GET3; 1.
DR Pfam; PF02374; ArsA_ATPase; 2.
DR PIRSF; PIRSF001327; Arsenical_pump-driving_ATPase; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Arsenical resistance {ECO:0000256|PIRNR:PIRNR001327};
KW ATP-binding {ECO:0000256|PIRNR:PIRNR001327};
KW Nucleotide-binding {ECO:0000256|PIRNR:PIRNR001327};
KW Reference proteome {ECO:0000313|Proteomes:UP000194358};
KW Translocase {ECO:0000256|PIRNR:PIRNR001327}.
FT DOMAIN 9..227
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 327..558
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 596 AA; 63482 MW; 1C66F5783787881C CRC64;
MEAGFLLQPT RHLFFTGKGG VGKTSLSTAA ALSLADRGKK VLLVSTDAAS NLDEMLGIEL
RNTPVPVPGA PGLSVLNIDP DTAAESYRQR VLGQMNAESS EEERSNVREQ LSGACTTEIA
SFDEFSSLLS DGAEHYDHIV FDTAPTGHTL RLLSLPKAWT GFLQGNDRGA SCLGPHSGLK
MQELRFKAAL EALSDPARTT VILVTRPDKG AMGEAARTSE ELHGLGLGNQ RLAINGVFHA
SDRTDAVACA IEDLGKQALD EMPEALRALP QDLVPLRPFD TVGLPALRAL LKPGTHHPVT
PHPIAAAENP TQVQGLDALA DDLAAADHGL VMVMGKGGVG KTTVAAALAL GLVQRGKTVH
LSTTDPAAHL SGTLSGDVPG LKVSRIDPKV ETQRYIDKIM ATRSPDLDPA EQALLLEDLQ
SPCTEEVAVF HAFSRIVGEG RSAFVVLDTA PTGHSMLLMD ATGAYHRQMT REFEGHGAAR
IVTPLMRLQD ANYTRIILVT LPEVTPVSQA AALQDDLRRA KIEPYAWVLN KSVLAAGTHD
PLLSARLAGE RKQIERMTAG LARRLFTLPW LTVPPIGFAA LSRLVSKAPE GATSEN
//
