ID A0A1Y2SC36_9GAMM Unreviewed; 414 AA.
AC A0A1Y2SC36;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Aromatic amino acid permease {ECO:0000256|RuleBase:RU367149};
GN ORFNames=Xvie_02224 {ECO:0000313|EMBL:OTA16180.1};
OS Xenorhabdus vietnamensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=351656 {ECO:0000313|EMBL:OTA16180.1, ECO:0000313|Proteomes:UP000194350};
RN [1] {ECO:0000313|EMBL:OTA16180.1, ECO:0000313|Proteomes:UP000194350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22392 {ECO:0000313|EMBL:OTA16180.1,
RC ECO:0000313|Proteomes:UP000194350};
RA Tobias N.J., Wolff H., Djahanschiri B., Pidot S.J., Stinear T.P.,
RA Ebersberger I., Bode H.B.;
RT "Systematic genetic and metabolomic analysis of Xenorhabdus and
RT Photorhabdus spp., highlights the requirements for a dual symbiotic and
RT pathogenic life style.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in transporting aromatic amino acids across the
CC cytoplasmic membrane. {ECO:0000256|RuleBase:RU367149}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU367149}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU367149}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC Mtr/TnaB/TyrP permease subfamily. {ECO:0000256|ARBA:ARBA00005452,
CC ECO:0000256|RuleBase:RU367149}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTA16180.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MUBJ01000010; OTA16180.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2SC36; -.
DR STRING; 351656.Xvie_02224; -.
DR OrthoDB; 18749at2; -.
DR Proteomes; UP000194350; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015173; F:aromatic amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR018227; Amino_acid_transport_2.
DR InterPro; IPR013059; Trp_tyr_transpt.
DR NCBIfam; TIGR00837; araaP; 1.
DR PANTHER; PTHR46997; LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED; 1.
DR PANTHER; PTHR46997:SF1; LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED; 1.
DR Pfam; PF03222; Trp_Tyr_perm; 1.
DR PRINTS; PR00166; AROAAPRMEASE.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|RuleBase:RU367149};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519,
KW ECO:0000256|RuleBase:RU367149};
KW Cell membrane {ECO:0000256|RuleBase:RU367149};
KW Membrane {ECO:0000256|RuleBase:RU367149};
KW Transmembrane {ECO:0000256|RuleBase:RU367149};
KW Transmembrane helix {ECO:0000256|RuleBase:RU367149};
KW Transport {ECO:0000256|RuleBase:RU367149}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 39..64
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 91..108
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 128..145
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 152..170
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 190..207
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 228..247
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 288..309
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 321..340
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 346..365
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 386..410
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
SQ SEQUENCE 414 AA; 45180 MW; 9D1487ED1D7B9DD0 CRC64;
MTIEVTQNLK RPSIFGGAMI IAGTAVGAGM FSIPIVTSGV WFTGSIILLV YTCVCMYFSG
LMILEANMNY PAGSSFHTVA KDLLGKSWSS LNGLSITFVL YILTYAYISA GSSILSHNIE
NIIPLPQSIS GLCFAFIVAF IVWLSTKAVD RLSTILIGGM VITFIMSVGG MFTEVKPTIL
FDQANTHPNY LPYALIALPY LLASFGYHGN IPGLVKYYHK DSKAVTSSLL YGTLITLAIY
ILWQYVIQGN IPREAFKQII ADGGNIGNLL QQMDITSDNT KITQFLNAFS YMALASSFLG
VSLGLFDYLA DFFKFNDSRK GRFKTALITF VPPTVLALVF PNGFLYAIGF AGLAATIWAV
IVPALMARAS RKRYPTSSYQ APGGNFLIIF VILFGLINAL AHTLSLFNLL PVYR
//
