ID A0A1Y2SH97_9GAMM Unreviewed; 700 AA.
AC A0A1Y2SH97;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=Xvie_01222 {ECO:0000313|EMBL:OTA17370.1};
OS Xenorhabdus vietnamensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=351656 {ECO:0000313|EMBL:OTA17370.1, ECO:0000313|Proteomes:UP000194350};
RN [1] {ECO:0000313|EMBL:OTA17370.1, ECO:0000313|Proteomes:UP000194350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22392 {ECO:0000313|EMBL:OTA17370.1,
RC ECO:0000313|Proteomes:UP000194350};
RA Tobias N.J., Wolff H., Djahanschiri B., Pidot S.J., Stinear T.P.,
RA Ebersberger I., Bode H.B.;
RT "Systematic genetic and metabolomic analysis of Xenorhabdus and
RT Photorhabdus spp., highlights the requirements for a dual symbiotic and
RT pathogenic life style.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTA17370.1}.
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DR EMBL; MUBJ01000004; OTA17370.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2SH97; -.
DR STRING; 351656.Xvie_01222; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000194350; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:OTA17370.1};
KW Cilium {ECO:0000313|EMBL:OTA17370.1};
KW Flagellum {ECO:0000313|EMBL:OTA17370.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 24..45
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 51..70
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 122..145
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 215..236
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 256..278
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 316..333
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 700 AA; 75753 MW; D46E7A75CD8E1503 CRC64;
MANLASLLRL SGNRLPGNIK GSQWQMLAGP VLILMILSMM VLPLPPFLLD LLFTFNIALS
IMVLLVAMFT RRTLDFAAFP TILLFSTLLR LSLNVASTRI ILMEGHTGSA AAGQVVEAFG
HFLVGGNFAI GIVVFVILIL INFMVITKGA GRIAEVGARF VLDGMPGKQM AIDADLNAGL
IGEDEAKKRR AEVTQEADFY GSMDGASKFV RGDAIAGLMI LVINIVGGLI VGVAQHGLTL
GDAAEAYTLL TIGDGLVAQL PALIISTAAG VIVTRVATDE DVGQQMVTQL FNNPKVMMLS
AGVLGLLGLV PGMPNFVFLL FTVALAGVGY FLLRKDKNPL AAQHEEMKAV EEQQQTAEAS
WSDVQLEDPL GMEVGYRLIP MVDFRQNGEL LGRISGIRKK FAQEVGYLPP VVHIRDNLEL
APASYRIMMK GVEIGRGEAH PGRWLAINPG GAVGELQGDL TTDPAFGLAA VWIDDSLREQ
AQVQGYTVVA ASTVVATHLN HLLSQHSSEL FGRQEAQQLF ERVSQEMPKL TEDFIPDVVS
LTTLHKVLQN LMAEQVPIRD MRTIIETLAE YAPAQKDPYE LTAMIRIALG RAIAQQWFPG
ADEIKVIGLD AGLERLLLQA LQNGGGLEPG LAESLERQAA EALERQEMLG APPVLLVNHA
LRPLLSRFLR RILPRLVVLS SLEITDNRQI RMTATIGGAR
//
