ID   A0A1Y2SQU3_9GAMM        Unreviewed;       445 AA.
AC   A0A1Y2SQU3;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Adenine permease {ECO:0000313|EMBL:OTA20492.1};
GN   ORFNames=Xbed_01296 {ECO:0000313|EMBL:OTA20492.1};
OS   Xenorhabdus beddingii.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=40578 {ECO:0000313|EMBL:OTA20492.1, ECO:0000313|Proteomes:UP000194204};
RN   [1] {ECO:0000313|EMBL:OTA20492.1, ECO:0000313|Proteomes:UP000194204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 4764 {ECO:0000313|EMBL:OTA20492.1,
RC   ECO:0000313|Proteomes:UP000194204};
RA   Tobias N.J., Wolff H., Djahanschiri B., Ebersberger I., Bode H.B.;
RT   "Deconstructing symbiosis and pathogenesis requirements using a combined
RT   genomic-metabolomic approach.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OTA20492.1}.
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DR   EMBL; MUBK01000008; OTA20492.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2SQU3; -.
DR   STRING; 40578.Xbed_01296; -.
DR   OrthoDB; 9808458at2; -.
DR   Proteomes; UP000194204; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        32..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        62..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        142..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        206..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        251..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        329..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        353..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        385..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        424..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   445 AA;  46894 MW;  354398A5EABB6C2D CRC64;
     MNTITSGSVN RQGLLQRVFK LEEHGTTVRT EMIAGLTTFL TMVYIVFVNP QILAVAGMDI
     KAVFVTTCLI AAVGSIMMGL VANLPVAVAP AMGLNAFFAF VVVGAMGISW QVAMGAIFWG
     AVGLLILTLF RIRYWMIANI PLSLRVGITS GIGLFIAMMG LKNAGIIVPN PDTIVSIGNF
     ASHNVLLGAL GFFIIAILAA RHFHAAVLVS IVATTGIGFM MGYVEYHGIF DLPPSVMSVV
     GNVDVKGALD IALAGVIFSF MLVSLFDSSG TLIGVTDKAG IADSNGTFPR MKQALYVDSI
     SSVAGSYIGT SSVTAYIESS SGVSVGGRTG LMAVVVGILF LLVMFISPLA SMVPAYATAG
     ALVYVGVLMT SSLTRVKWHD LTESVPAFIT AVMMPFSFSI TEGIALGFIA YCAMKLGTGK
     WREIGPCVFV VTLLFVLKMV FVDAH
//