ID   A0A1Y2STI4_9GAMM        Unreviewed;       573 AA.
AC   A0A1Y2STI4;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Murein L,D-transpeptidase {ECO:0000313|EMBL:OTA21677.1};
GN   ORFNames=Xbed_00427 {ECO:0000313|EMBL:OTA21677.1};
OS   Xenorhabdus beddingii.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=40578 {ECO:0000313|EMBL:OTA21677.1, ECO:0000313|Proteomes:UP000194204};
RN   [1] {ECO:0000313|EMBL:OTA21677.1, ECO:0000313|Proteomes:UP000194204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 4764 {ECO:0000313|EMBL:OTA21677.1,
RC   ECO:0000313|Proteomes:UP000194204};
RA   Tobias N.J., Wolff H., Djahanschiri B., Ebersberger I., Bode H.B.;
RT   "Deconstructing symbiosis and pathogenesis requirements using a combined
RT   genomic-metabolomic approach.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004752}.
CC   -!- SIMILARITY: Belongs to the YkuD family.
CC       {ECO:0000256|ARBA:ARBA00005992}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OTA21677.1}.
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DR   EMBL; MUBK01000002; OTA21677.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2STI4; -.
DR   STRING; 40578.Xbed_00427; -.
DR   OrthoDB; 9778545at2; -.
DR   UniPathway; UPA00219; -.
DR   Proteomes; UP000194204; Unassembled WGS sequence.
DR   GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProt.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd16913; YkuD_like; 1.
DR   Gene3D; 2.40.440.10; L,D-transpeptidase catalytic domain-like; 1.
DR   Gene3D; 1.10.101.10; PGBD-like superfamily/PGBD; 1.
DR   InterPro; IPR005490; LD_TPept_cat_dom.
DR   InterPro; IPR045380; LD_TPept_scaffold_dom.
DR   InterPro; IPR002477; Peptidoglycan-bd-like.
DR   InterPro; IPR036365; PGBD-like_sf.
DR   InterPro; IPR036366; PGBDSf.
DR   InterPro; IPR038063; Transpep_catalytic_dom.
DR   PANTHER; PTHR41533; L,D-TRANSPEPTIDASE HI_1667-RELATED; 1.
DR   PANTHER; PTHR41533:SF1; L,D-TRANSPEPTIDASE YCBB-RELATED; 1.
DR   Pfam; PF01471; PG_binding_1; 1.
DR   Pfam; PF20142; Scaffold; 1.
DR   Pfam; PF03734; YkuD; 1.
DR   SUPFAM; SSF141523; L,D-transpeptidase catalytic domain-like; 1.
DR   SUPFAM; SSF47090; PGBD-like; 1.
PE   3: Inferred from homology;
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..573
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012418037"
FT   DOMAIN          88..218
FT                   /note="L,D-transpeptidase scaffold"
FT                   /evidence="ECO:0000259|Pfam:PF20142"
FT   DOMAIN          243..299
FT                   /note="Peptidoglycan binding-like"
FT                   /evidence="ECO:0000259|Pfam:PF01471"
FT   DOMAIN          330..497
FT                   /note="L,D-transpeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF03734"
FT   REGION          36..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   573 AA;  64531 MW;  773680E48D34DE31 CRC64;
     MAKNSVRLLK VSFICSALAV SEGTFATQQN DQASSDVQQL AGEQKKEGSL ASSDQTIPIS
     PIKSIGENRK QLQNGLPQQV KPVFLDRLVT LYTANEMKLL WTDKKAIQQF ESQLFEISLA
     GFQPQFEKWL VQLDSPELSD MGRDIILSDA MLGYLHFING VKKKGDSWLY SKTPYKVDLP
     PAHLIDKWQQ HINNHDTLTY ITALSPHHPM YENMRKEMLA QLADKQPWTE FSLKGTLRPG
     QSSESVIALR KILVRSGTLE PSAIKSDNKI YAKELTAAVK RFQTLHGLSA DGVIGQSTKI
     WLNTTPQMRA RIMALNIQRL RIIPGDIPTG ILVNIPNYSL FYYSDGKEVL SSKVVVGRPS
     RKTPIMSSQL NNVVINPPWT VPTSMTRKDI APRAMRDPNY FRTRGYTVFS SWSNDAKVID
     PLSINWGVIT PDNFPYRIRQ APGPTNSLGR FKFNMPNSEA IYLHDTPNQA SFSREMRAVS
     SGCVRVNKAP ELANMLLGDA GWNKDKVKGS LKTWGTKYVN IPQKIPVFLY YQTAWVDEGG
     VPQYRADIYG YDMNARQPSE WLSKILAARK DLS
//