ID A0A1Y2VC99_9PEZI Unreviewed; 917 AA.
AC A0A1Y2VC99;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|SMART:SM00913};
GN ORFNames=M434DRAFT_267600 {ECO:0000313|EMBL:OTA94378.1};
OS Hypoxylon sp. CO27-5.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Hypoxylaceae; Hypoxylon.
OX NCBI_TaxID=1001938 {ECO:0000313|EMBL:OTA94378.1, ECO:0000313|Proteomes:UP000194361};
RN [1] {ECO:0000313|EMBL:OTA94378.1, ECO:0000313|Proteomes:UP000194361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO27-5 {ECO:0000313|EMBL:OTA94378.1,
RC ECO:0000313|Proteomes:UP000194361};
RX PubMed=28078400; DOI=10.1007/s00253-017-8091-1;
RA Wu W., Davis R.W., Tran-Gyamfi M.B., Kuo A., LaButti K., Mihaltcheva S.,
RA Hundley H., Chovatia M., Lindquist E., Barry K., Grigoriev I.V.,
RA Henrissat B., Gladden J.M.;
RT "Characterization of four endophytic fungi as potential consolidated
RT bioprocessing hosts for conversion of lignocellulose into advanced
RT biofuels.";
RL Appl. Microbiol. Biotechnol. 101:2603-2618(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC subfamily. {ECO:0000256|ARBA:ARBA00038423}.
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DR EMBL; KZ112457; OTA94378.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2VC99; -.
DR STRING; 1001938.A0A1Y2VC99; -.
DR Proteomes; UP000194361; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000194361};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 32..109
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|SMART:SM00913"
FT REGION 353..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 917 AA; 102159 MW; 8DBB9DA14AA0F3FD CRC64;
MAWQPSPESL STLAACLKDS LSGFDKAAQK QAEIMLTQAK SSPDINNYLV YLFSSPNPPN
GLQCSPEDYF LIRSSAAIML KNNIKMSSKP VPESSLALIK MGIPMCLQDK NAQIRNYAGV
IATEMIRRGG IMSWPELLPE LLKMIGNETG QVTNEGQEGA MAAMAKICED NTKMLERELN
GERPLNFILP KLIQATKSPL PKVRAYALTA INVFTARKSQ AMLNSIDDLL QHLFALSSDS
NNDVRRQVCR AFSQLVESRP DKIQPHLPGL VDYIIMQQKS DDEDLATDAA EFWLTVGEHE
HLWNSLTPYI NKIIPVLLDC MVYSAEDMAL LGGASDDEDE EDLEQDIKPQ FAKKSATRQA
NGGEGSADPA QNGNAYEKLA SMDDDLEEGE IEDFEDGDDA NPDERWTLRK CSAAALDVFA
RDFRDPVFES ILPYLSKNLR HQDWPYREAA VLALGAVAEG CLNVVTPHLP QLVPYLISLL
NDPEPVVRQI TCWTLGRYSS WAADLTDPTQ KRLYFEPMME GILTKMLDSN KKVQEAGASA
FANLEEKAGK RLEPYSLPII QQYVQCFKKY KDRNMYILYD CVQTLAEHIG PVLARPDLVN
ELMPALIERW TKVSDQSREL FPLLECLSYV AMALNDAFTP YAQPIFIRCV NIIHQNLEAS
LALANDPTLD APDKDFLVTS LDLLSAIIQA LDPAKSSVLV QESQPAFFEL LTFCMEDPSD
EVRQSAYAVL GDCAKYVFEQ LQPALPSIFP ILLRQLDLDS ILDEDIDSGF GVVNNACWSA
GEIAIRHKSN MAPYVPELFQ RFIEIITNQG IPKGVTENAA IALGRLGVGN ADLLAPELAN
FAEHFLTSMD EVDPSDEKAT AFRGFTAIVE KNPMAMEKSL LHFFTSIAQY RDLKLRSETK
SGLHEDFQKV SNIILVH
//
