ID   A0A1Y2VJW8_9PEZI        Unreviewed;       994 AA.
AC   A0A1Y2VJW8;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein {ECO:0000259|Pfam:PF13640};
GN   ORFNames=M434DRAFT_26350 {ECO:0000313|EMBL:OTA97951.1};
OS   Hypoxylon sp. CO27-5.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Hypoxylaceae; Hypoxylon.
OX   NCBI_TaxID=1001938 {ECO:0000313|EMBL:OTA97951.1, ECO:0000313|Proteomes:UP000194361};
RN   [1] {ECO:0000313|EMBL:OTA97951.1, ECO:0000313|Proteomes:UP000194361}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO27-5 {ECO:0000313|EMBL:OTA97951.1,
RC   ECO:0000313|Proteomes:UP000194361};
RX   PubMed=28078400; DOI=10.1007/s00253-017-8091-1;
RA   Wu W., Davis R.W., Tran-Gyamfi M.B., Kuo A., LaButti K., Mihaltcheva S.,
RA   Hundley H., Chovatia M., Lindquist E., Barry K., Grigoriev I.V.,
RA   Henrissat B., Gladden J.M.;
RT   "Characterization of four endophytic fungi as potential consolidated
RT   bioprocessing hosts for conversion of lignocellulose into advanced
RT   biofuels.";
RL   Appl. Microbiol. Biotechnol. 101:2603-2618(2017).
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DR   EMBL; KZ112422; OTA97951.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2VJW8; -.
DR   Proteomes; UP000194361; Unassembled WGS sequence.
DR   Gene3D; 2.60.120.620; q2cbj1_9rhob like domain; 1.
DR   InterPro; IPR044862; Pro_4_hyd_alph_FE2OG_OXY.
DR   PANTHER; PTHR33099; FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR33099:SF7; MYND-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13640; 2OG-FeII_Oxy_3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000194361}.
FT   DOMAIN          134..217
FT                   /note="Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG
FT                   dioxygenase"
FT                   /evidence="ECO:0000259|Pfam:PF13640"
FT   REGION          908..927
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          943..994
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        945..974
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   994 AA;  113190 MW;  AB8940BD95CB736E CRC64;
     MDSGGANRNN VASAKFDKSE LLNALDSIYP ASSFSGFAPV QCHDPDIFVQ DVGRIDLPLS
     ETQAKELALK SHQAPYGKGS ETIVDTSVRN TWELNPDQFE IRAPDWSKVL DAVLAYVRKK
     LAIRPLISAE LYKMLLYEEG AMFKAHTDTE KVPRMFGTLV ISLPSSHEGG DVIVTHQGYS
     QRYETSRHDM ACAFWFSDVS HEVLPVKRGY RWVLTYNLAI EQSAHVPTAD GFVDHQEIRR
     VLQSWLQEVN TGSRKASPLY FVLNHKYTEA NISYEGLKPP DLDVVESLRE VCPELGFDLF
     LTTLERKESG LPQDGRFDPY YRDRYDRYDE SEEDDCGIRP LEEVYDVSYC SKYVFDLNGN
     KLVSYVPLNS DNILHEDPFE DGPDQEDYEG YMGNSGPSAT HWYRLSAVII IPCRGTVSFL
     SSTDPDYLIP NYPSNDDFQA LCTYFTTQCV EASERATAQL YEFVRTTCYP SLSPPKAQRL
     AGGDLLKVLQ ASILAPKPEL LDFILSKSKA QVPIDFFAWI KGKHDNSRIS TEKFKRGFLH
     ALRTQATLSE QYQAILAVEG EMDPTDEIHD IISRAVNECI HSYPIYRPLF EEDGPALFDL
     SLYYHDFSYL EEIVLPIVEA RRKSTAFVLG FIRALYQSMK RQQISQDRAQ PMYEYAARLA
     LQGIKLASLA ISDIPLSQKV QETERTGLTK QYMTYDSMLK FVSTLVALKL ETHLELLAAK
     LHSEAEQINE QAFKELWIPL FQTLLPILAQ QKINLLAGHW IQMFQTLLKA YLKNYVRDKP
     LKTNMSREKV SCYCADCKMD LNPFLASSNR IGRFRMGEKR RRHLETKLYQ AHIDCTAHTE
     RSGIPYTLVV TKTTRLYDAA LDTWWWRRNL AEDQLETFDQ DLLRSVLDNQ FDEIMSMKFL
     ERQEQPTMFG NSLSSSSRHP PIQRPSALNN SADQLRELNA EIARLAGPSS TTPNPSSTPK
     PSSSTPSRPS QMIPNPIAGT KRKYIEVIDL TGDD
//