ID A0A1Y2W189_9PEZI Unreviewed; 576 AA.
AC A0A1Y2W189;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=ENTH domain-containing protein {ECO:0000259|PROSITE:PS50942};
GN ORFNames=M426DRAFT_12331 {ECO:0000313|EMBL:OTB03613.1};
OS Hypoxylon sp. CI-4A.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Hypoxylaceae; Hypoxylon.
OX NCBI_TaxID=1001833 {ECO:0000313|EMBL:OTB03613.1, ECO:0000313|Proteomes:UP000242955};
RN [1] {ECO:0000313|EMBL:OTB03613.1, ECO:0000313|Proteomes:UP000242955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CI-4A {ECO:0000313|EMBL:OTB03613.1,
RC ECO:0000313|Proteomes:UP000242955};
RX PubMed=28078400; DOI=10.1007/s00253-017-8091-1;
RA Wu W., Davis R.W., Tran-Gyamfi M.B., Kuo A., LaButti K., Mihaltcheva S.,
RA Hundley H., Chovatia M., Lindquist E., Barry K., Grigoriev I.V.,
RA Henrissat B., Gladden J.M.;
RT "Characterization of four endophytic fungi as potential consolidated
RT bioprocessing hosts for conversion of lignocellulose into advanced
RT biofuels.";
RL Appl. Microbiol. Biotechnol. 101:2603-2618(2017).
CC -!- SIMILARITY: Belongs to the epsin family.
CC {ECO:0000256|ARBA:ARBA00010130}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KZ111557; OTB03613.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2W189; -.
DR STRING; 1001833.A0A1Y2W189; -.
DR InParanoid; A0A1Y2W189; -.
DR OrthoDB; 1532at2759; -.
DR Proteomes; UP000242955; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR CDD; cd16991; ENTH_Ent1_Ent2; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR PANTHER; PTHR12276:SF110; FI19443P1; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00726; UIM; 2.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50330; UIM; 1.
PE 3: Inferred from homology;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000242955}.
FT DOMAIN 10..143
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 152..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..238
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..464
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..576
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 576 AA; 64414 MW; 69BFFD8CF5AB1392 CRC64;
MSKVMRSVKN VTKGYSSVQV KVREATSNDP WGPTGTQMSE IAQLTYNSST EFYDIVDMLD
KRLNDKGKNW RHVLKALKVL DYCLHEGSEL VVTWARKNIY IIKTLREFVY IDEDGRDVGQ
NVRVAAKELT ALILDEERLR AERSDRKTWK SRVTGIEEFS EGPTVPAQRR QRPRRHSDDE
DDAEYKLAIE ASKYQEEEDR KKRASHPGGE DDDDLAKAIK LSKEEEERRR RELEENNASS
LFDDDPQPSN VPQPTGMNMG YQQGSNVDWL GNPIDQNQMM QQQQQQQQQP TGYVNNAYTG
YPANGYSNGF NNGFQPQPTG MYDPYGQQNN NFLQPQPQQQ QQQQLPMQPT GYNPYAQQPQ
FQQPQPTASP EPAVQSGSNN PWASNNNQAQ SLKPTPTGSN NPFATGFGRP QTAKTPTMPT
LSSLQALPEQ KSLQTFTPPP QPQQQLQPQP SFNQTQQPQK PMSEHEQRLN ALLASGDGMD
TFGNTGDLRI PAQHTAPGTF VNSAGANAQR LTAEATGSNP FLRQQFTGMP TVSYGQPQMP
AATGPVSMNG YGGGSNPFAA RPQQQQNNQG QDLIQF
//
