ID A0A1Y2W2C6_9PEZI Unreviewed; 655 AA.
AC A0A1Y2W2C6;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=WH1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=M426DRAFT_23285 {ECO:0000313|EMBL:OTB03964.1};
OS Hypoxylon sp. CI-4A.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Hypoxylaceae; Hypoxylon.
OX NCBI_TaxID=1001833 {ECO:0000313|EMBL:OTB03964.1, ECO:0000313|Proteomes:UP000242955};
RN [1] {ECO:0000313|EMBL:OTB03964.1, ECO:0000313|Proteomes:UP000242955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CI-4A {ECO:0000313|EMBL:OTB03964.1,
RC ECO:0000313|Proteomes:UP000242955};
RX PubMed=28078400; DOI=10.1007/s00253-017-8091-1;
RA Wu W., Davis R.W., Tran-Gyamfi M.B., Kuo A., LaButti K., Mihaltcheva S.,
RA Hundley H., Chovatia M., Lindquist E., Barry K., Grigoriev I.V.,
RA Henrissat B., Gladden J.M.;
RT "Characterization of four endophytic fungi as potential consolidated
RT bioprocessing hosts for conversion of lignocellulose into advanced
RT biofuels.";
RL Appl. Microbiol. Biotechnol. 101:2603-2618(2017).
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DR EMBL; KZ111554; OTB03964.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2W2C6; -.
DR STRING; 1001833.A0A1Y2W2C6; -.
DR InParanoid; A0A1Y2W2C6; -.
DR OrthoDB; 3837860at2759; -.
DR Proteomes; UP000242955; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR CDD; cd01205; EVH1_WASP-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR033927; WASPfam_EVH1.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR45691; PROTEIN DIAPHANOUS; 1.
DR PANTHER; PTHR45691:SF6; PROTEIN DIAPHANOUS; 1.
DR Pfam; PF00568; WH1; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50229; WH1; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000242955}.
FT DOMAIN 17..129
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT DOMAIN 568..588
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 120..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 240..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..262
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..347
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..375
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..551
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..649
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 655 AA; 68409 MW; C945531D5F49463F CRC64;
MPSILSEEDK ETVRRVVPKH TNKIQAVAVA RLYVAHPNPH KWTYTGLQGA IVLSNDLVGN
TYWLKLVDVS PAGRGVIWDQ EIFDTWSYNQ DRTFFHTFEL EDCLAGLSFV DEKEAKQFKK
KMDEREKNAS KATKNTPFGG PTQQPVKSGF FSGIFGGHRH SSAPTPPESP RNSLPPAQPQ
EKTPTGNTNG FHKPSSRFAK LEAYDANWRE NFGNFLSEQG LTDEFIRENQ DFIVEFLKEQ
GTGPSHRTHH APPPPPPPPS GSTSTLNGSH SHGRAPPPPP PPPGGGRATE AVSTSGSRRG
VPPPPPAPRR SGKMEIVHVG REPTPPREPV PPQEPVPPRP RFNAPPPLPD AGKFANEQPA
PRAPPGPAPP PRPPKTPIDD TDEKSSGHKF GVPPVFTGQR VNTNAPPPAP ARGPVPPPPP
REQPQSPPPP PLPPSLPPKL PASSAPPPPP LPPAASRPTP APPRSTPAPP APPAPPLPPT
NAPVPPPLPQ SSAPPPPPPL PGVGGGTGAP PPAPPPPPPP PGGAGIPPPP PPPPPPAGIP
MPPPPPPNRD SGYSSGVPAP AIPSADSGRS AVLDSIQKAG GIGALKKVDR SQIRDRSGAT
VGGGSDTGPH GSGLPPAGIA PGGGGGGMAD ALAAALQKRK ERVRDSDDEK SDDEW
//
