ID A0A1Y2W7H1_9PEZI Unreviewed; 627 AA.
AC A0A1Y2W7H1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 28-JUN-2023, entry version 20.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OTB04969.1};
GN ORFNames=M426DRAFT_73111 {ECO:0000313|EMBL:OTB04969.1};
OS Hypoxylon sp. CI-4A.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Hypoxylaceae; Hypoxylon.
OX NCBI_TaxID=1001833 {ECO:0000313|EMBL:OTB04969.1, ECO:0000313|Proteomes:UP000242955};
RN [1] {ECO:0000313|EMBL:OTB04969.1, ECO:0000313|Proteomes:UP000242955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CI-4A {ECO:0000313|EMBL:OTB04969.1,
RC ECO:0000313|Proteomes:UP000242955};
RX PubMed=28078400; DOI=10.1007/s00253-017-8091-1;
RA Wu W., Davis R.W., Tran-Gyamfi M.B., Kuo A., LaButti K., Mihaltcheva S.,
RA Hundley H., Chovatia M., Lindquist E., Barry K., Grigoriev I.V.,
RA Henrissat B., Gladden J.M.;
RT "Characterization of four endophytic fungi as potential consolidated
RT bioprocessing hosts for conversion of lignocellulose into advanced
RT biofuels.";
RL Appl. Microbiol. Biotechnol. 101:2603-2618(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
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DR EMBL; KZ111546; OTB04969.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2W7H1; -.
DR STRING; 1001833.A0A1Y2W7H1; -.
DR InParanoid; A0A1Y2W7H1; -.
DR OrthoDB; 1358357at2759; -.
DR Proteomes; UP000242955; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12829; Alr1p-like; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR044089; Alr1-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR PANTHER; PTHR21535:SF55; MAGNESIUM TRANSPORTER ALR1-RELATED; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242955};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 569..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 627 AA; 70165 MW; 29CDD739B4F2106B CRC64;
MSDYEGTASG SGYDTPVPEL DDHRHQASST QRQDRPRRGT VDTLYGSRQH LQLLDPHSPS
DIRVRDFEEA IIDEDDGNVS PMATHGRRLT FNSTNEPPQR AVSPPNSVKA FAEARRRERA
LSITDGRQRP EEGDGLHRTQ SNVSRISRVS QESTRSKHGT YVADDGASLA TNKTAEEDVC
FPMQDEHHSD QLHIDFDYLE NFVASENVAR KESFDARGAI RVFPNLRPDT AVSQPAPMVT
VDGDFVNSAS AGGPPESADP ASENATQHIN KETHLDPNRF SFFSSAWEST IHAAEFGDLV
LPGEDLRGLF TFPREESDGV WWLNVNRPTE EEVRTLCKAF GVHPLTIEDI TTQEAREKIE
IFPSYYFASF QSITVVEEED GPDYEPYNIY VVVFRQGTLS FSFVPNTHAA QVRKRISSLK
EYVSLSSDWI CYALIDNIVD SFAPAIRRVE LLTEGIEDSV FVARPGEMHM FLRKIGGVRK
NTLAIMRGLG GKADVLKGFT KRCNEDYKVT PRMDIGMYLG DIQDHVVTMM TNLAHFEKIL
SRSHSNYLAL LTVDSITQGT ETNRVLSKIT LIASLVVPLN IITGLFGMNV HVPFQDDGNT
RAFYVILACL VVICSSCIFC ARKFRLI
//
