ID A0A1Y2W9F6_9PEZI Unreviewed; 848 AA.
AC A0A1Y2W9F6;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Choline/carnitine acyltransferase domain-containing protein {ECO:0000259|Pfam:PF00755};
GN ORFNames=M426DRAFT_57019 {ECO:0000313|EMBL:OTB05436.1};
OS Hypoxylon sp. CI-4A.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Hypoxylaceae; Hypoxylon.
OX NCBI_TaxID=1001833 {ECO:0000313|EMBL:OTB05436.1, ECO:0000313|Proteomes:UP000242955};
RN [1] {ECO:0000313|EMBL:OTB05436.1, ECO:0000313|Proteomes:UP000242955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CI-4A {ECO:0000313|EMBL:OTB05436.1,
RC ECO:0000313|Proteomes:UP000242955};
RX PubMed=28078400; DOI=10.1007/s00253-017-8091-1;
RA Wu W., Davis R.W., Tran-Gyamfi M.B., Kuo A., LaButti K., Mihaltcheva S.,
RA Hundley H., Chovatia M., Lindquist E., Barry K., Grigoriev I.V.,
RA Henrissat B., Gladden J.M.;
RT "Characterization of four endophytic fungi as potential consolidated
RT bioprocessing hosts for conversion of lignocellulose into advanced
RT biofuels.";
RL Appl. Microbiol. Biotechnol. 101:2603-2618(2017).
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
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DR EMBL; KZ111543; OTB05436.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2W9F6; -.
DR STRING; 1001833.A0A1Y2W9F6; -.
DR InParanoid; A0A1Y2W9F6; -.
DR OrthoDB; 1429709at2759; -.
DR Proteomes; UP000242955; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 1.10.275.20; Choline/Carnitine o-acyltransferase; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR042572; Carn_acyl_trans_N.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF29; MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000242955};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 73..718
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT REGION 20..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 598..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..616
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..754
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 379
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 848 AA; 94246 MW; C0553CE084EE6C3D CRC64;
MPTQVRIFAM PKSLGETLSA SSSAPVSLLT ERTKPEKPAS PEIKSLVPIM ETIPEKPKEG
GITFASQDSL PKLPIPELEQ TCKKYLAALK PLQGAREHSE TKFAVQDFLK KDGPELQKKL
QEYAVGKTSY IEQFWYDSYL NFDNPVVLNL NPFFLLEDDP TPARNNQVTR AASLVVSALE
FVRAVRREEL PPDTVKGTPL DMYQYSRLFG TARVPTENGC QIEQDPDSKH IVALCHGQIY
WFDVLDDNSD LIMSERDIAI NLQTITDDAA QTPIQEAAKG ALGILSTENR KTWSGLRDVL
TKEEGSNNAD CLGIVDSALF VLCLDYTEPS TAAALCQNML CGTNDVVKGV QVGTCINRWY
DKLQIIVCKN GSAGINFEHT GVDGHTVLRF ASDLYTDTIL RFARTINGKA PSLWKTTSPD
PSKRDPESFG DVTTTPHKLE WDISPELNIA IRFAETRLAD LISQNEFECL DFAGYGKNYI
TSAGFSPDAF VQMAFQAAYY GLYGRIESTY EPAMTKAFLH GRTEAIRTVT EESVNFCQTF
WADNSAEAKA EALRKACQQH TNSTRECSKG RGCDRHLYAL FCLWQRYLEG DASRSNSSLG
YSSPVENGSE QGGSVVGSPG KESVLSNEEF RTRQRGDSTN SRYQENMVPA IFADNGWDKL
NNTILSTSNC GNPSLRQFGF GPTSGGGFGI GYIIKEEGIN ICVASKHRQT KRFVDTLESY
LLEIRRILRI TNRKGTTSRQ TRAREIDPDK PRTSHHRVKT RGRMITGTES LRALARSSTG
TRSPTEESLM MSEDDELGGY GFFDAGMLLQ ALKARGEALD HQNESKAERA AANARRREIG
KKLRLVEY
//
