ID A0A1Y2WGJ6_9PEZI Unreviewed; 1394 AA.
AC A0A1Y2WGJ6;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=PH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=M426DRAFT_317559 {ECO:0000313|EMBL:OTB08046.1};
OS Hypoxylon sp. CI-4A.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Hypoxylaceae; Hypoxylon.
OX NCBI_TaxID=1001833 {ECO:0000313|EMBL:OTB08046.1, ECO:0000313|Proteomes:UP000242955};
RN [1] {ECO:0000313|EMBL:OTB08046.1, ECO:0000313|Proteomes:UP000242955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CI-4A {ECO:0000313|EMBL:OTB08046.1,
RC ECO:0000313|Proteomes:UP000242955};
RX PubMed=28078400; DOI=10.1007/s00253-017-8091-1;
RA Wu W., Davis R.W., Tran-Gyamfi M.B., Kuo A., LaButti K., Mihaltcheva S.,
RA Hundley H., Chovatia M., Lindquist E., Barry K., Grigoriev I.V.,
RA Henrissat B., Gladden J.M.;
RT "Characterization of four endophytic fungi as potential consolidated
RT bioprocessing hosts for conversion of lignocellulose into advanced
RT biofuels.";
RL Appl. Microbiol. Biotechnol. 101:2603-2618(2017).
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DR EMBL; KZ111528; OTB08046.1; -; Genomic_DNA.
DR STRING; 1001833.A0A1Y2WGJ6; -.
DR InParanoid; A0A1Y2WGJ6; -.
DR OrthoDB; 2027807at2759; -.
DR Proteomes; UP000242955; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR CDD; cd07609; BAR_SIP3_fungi; 1.
DR CDD; cd13280; PH_SIP3; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR039463; Sip3/Lam1_BAR.
DR InterPro; IPR042067; Sip3_PH.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR14248; CYCLIN Y, ISOFORM A; 1.
DR PANTHER; PTHR14248:SF18; CYCLIN Y, ISOFORM A; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF16016; VASt; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS51778; VAST; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000242955};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 306..405
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 913..1084
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT REGION 458..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 626..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 850..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1394 AA; 155833 MW; D6F9D40AE8699850 CRC64;
MATPTTQPTP APPSTKFPNP SIPVILHEAG LDSPSFRSSS QYFAEQVDAI ERWLEGYVRT
TAKLSYDLLG LEETIHTYLG KIIPPPNINV VDNDYAALAL KRFSEGSREW WMQLLNAARK
LDSMSVEPVR NFLQGDLRNF KETRKALEQT QKVFDTTLAR YVGQSKTKEP SSLREDAFAV
YETRKAYLKA SMDFCFFAPQ FRVNLDKLLV RVCSDQWREM KKSRDTAGSF ARFGHEMDRV
RGWSKEMELS EPTFKRELQI ARRDIGESTL AAFKPSREID DYSASTVPFL GSRGPLSVST
GQTTLISEKQ GWLFLRTITG KPSRTNWIRR WYYCRDGIFG WLVNGPQGVL QGDEIGVLLC
NVKPAVGEER RFCFELKTKN QTLLLQAETQ AQLIEWLEVF EVAKKKAFEA SVSRDSSSLP
GGVDPAFSIT PPSLPEFSAM VLDAQLDDGA GTERADTLAA PTPGNLIPRP SFDITTAPPK
RSVTSLARED GETGREHAAR IMQKLDLHRK ATFTSSTDVG STSGPGPTTG IAGLISASHG
LLPGYPAANS RQQQALPVLP GPETQPGSLA PTTLAKPPAT TNLSKTAVVY SGDRVFNANT
NQSLPTAIMA NYWGSNAWGQ EYTPKANRAD QDRDDPFGPN SPSIKMTTVG DGEEIKTPTS
AHKKAISMDA RINHPKVILP AAEKPPPETF PPSYPIELKT NSAQFRLLFP GVPLDEKLVL
VFRASWTSTS EPEHDVPQMA GNGRIYVTSD NMYFYGHQMG LVITYTINLD AITEVTAAPG
RDCDFIFLHL GADDIGYTRI TIKTFLEDLD LLHARLNLLI DDLQAEEPME LSELIKALIS
LEREEDIDRR SPSMDSWEEV SEHTPMDNGT VAGRAVSPRN HHTGYRSRGH SLRKPLPKFQ
LPTHPVIYEP EDMQRKVAER NFEISAKACF HVLFGDKSFV FPKLYFERRA QHIAQGPWKP
NEAGNLQRQF RFSVSYTTRL GRNRDEEVVD QQTIELFSDH VTYVVTHVKT PWHLPHAHGF
KLVTKTVITH VAKSKCKLAI FTKVAWSKPP ALAKNMVERQ ALDDAGQDAE ELAEVATDQV
RKLGHHSRTK RAIQVYGNVG LQSQVVVFTP GESEMSKKAQ INPRTLGQML FETIRSFADS
VALSLMMWSF AAVKKLWDVV TAQRIILALL GFSILTNLIF SSQSTSAWWG ERRAASFMNR
VGVSPNVIMS KAIYIADLDE AARSSAVLPT WPQDSYCYST FRSITNASDV DTPYEYAGAS
LSWSSSRATA RRLRQTRQKL GTYRHDLLVA MRMVNSVERE MLHAEWENWL LDENHRCGQV
EVVLAAWNSS ADSGLKGEIL RQQKVLGGGD KEKDETKRKN LQLWHDEYCG SCKHDRESLL
QERESLSLSA VSAA
//
