ID   A0A1Y2XED5_9PEZI        Unreviewed;      1218 AA.
AC   A0A1Y2XED5;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Hydantoinase B/oxoprolinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=K445DRAFT_326976 {ECO:0000313|EMBL:OTB19549.1};
OS   Daldinia sp. EC12.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Hypoxylaceae; Daldinia.
OX   NCBI_TaxID=1001832 {ECO:0000313|EMBL:OTB19549.1, ECO:0000313|Proteomes:UP000243732};
RN   [1] {ECO:0000313|EMBL:OTB19549.1, ECO:0000313|Proteomes:UP000243732}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EC12 {ECO:0000313|EMBL:OTB19549.1,
RC   ECO:0000313|Proteomes:UP000243732};
RX   PubMed=28078400; DOI=10.1007/s00253-017-8091-1;
RA   Wu W., Davis R.W., Tran-Gyamfi M.B., Kuo A., LaButti K., Mihaltcheva S.,
RA   Hundley H., Chovatia M., Lindquist E., Barry K., Grigoriev I.V.,
RA   Henrissat B., Gladden J.M.;
RT   "Characterization of four endophytic fungi as potential consolidated
RT   bioprocessing hosts for conversion of lignocellulose into advanced
RT   biofuels.";
RL   Appl. Microbiol. Biotechnol. 101:2603-2618(2017).
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
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DR   EMBL; KZ112929; OTB19549.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y2XED5; -.
DR   STRING; 1001832.A0A1Y2XED5; -.
DR   OrthoDB; 674at2759; -.
DR   Proteomes; UP000243732; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000243732}.
FT   DOMAIN          1..112
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          132..424
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          437..617
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          636..1169
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
SQ   SEQUENCE   1218 AA;  132195 MW;  741FCC169C76F64E CRC64;
     MGTTVATNAL LERKGTRHAF VVNQGFGDLL EIGYQSRPKL FELGIKKPEL LYETGITGDI
     LRIVRPLNDT EVREKLAKIK AEGIETLAIC LAHSYLYPNH ENRIAEIAKE MGFTHISTSS
     SVGANMIKMI SRGSSASADA YLTPEITRYV SGFAKVFADG NLDGVSCEFM QSDGGLVNHK
     NFNGLKGILS GPAGGVVGHA RTSFDGTSPI VGFDMGGTST DVSRYGGSFE HVFETTTAGV
     SIQSPQLDIN TVAAGGGSML FWRDGLFKVG PDSAGAHPGP ASYRKGGPLT VTDANLFLGR
     LIPDYFPKIF GPTENLPLDI DIVVQKFEEL TAQINADTGR SMTPLEVAHG FIDVANESMS
     RPIRALTEAK GFETQQHALA TFGGAGGQHA CEIAKKLGIK RIVIHKYSSI LSAYGMALAE
     VVQEAQEPSS EILSEESLTR LMARMQDLKA KVTEGLLAQG IQEAAIEHEQ YLNLRYQGTD
     TNFMILAPVD GDWRSALEKE HLRELSFVFP RGKKVHVDDV RVRGVGKSTE VSHDNSKLVK
     ELESNFSEVK EGEDRIVSSL TQAYFSEGGL QPTKVFRLNV IAPGSIVNGP AIIIDNTQTI
     VVVPGSQARV LTSHVVINLV DEKPQQSQEE QELVVDPIKL SIFGHRFMSI AEQMGRALQK
     TSVSINIKER LDFSCAIFSP DGQLVANAPH VPVHLGSMSY AVKYQHNLHK GKLRPGDVLV
     TNHPEAGGTH LPDITVITPV FDTDGETICF YTASRGHHLD IGGYRGNSMP PDSTELWQEG
     AAIKSFFLVR DNHFDEDGIV KILLEPGKYP NSSGSRRLAD NLSDLKAQVA ANNKGSNLIK
     ALMEEYGKHT VHFYMAKIQE NAEVSVRNYL RSAYKRYGSK PLKAKQFLDN GSMMKVSITI
     DESGFGTFDF TGTSCEMLSN MNAPPAITYS ALIYTLRLLI GSDIPLNQGC LAPTKVILPK
     NCFLNPSSGP AVCCGNTLTS QRLVDLLLNA FRAASGSQGC MNCFGFFGNC RDDSGEPQSG
     FGFSYGETIC GGEGAGPTWH GASAVQIHMT NTRTTDIEII EKRYPVLVRE FSIRKGSGGR
     GKYSGGCGIV RDWECRHPLT FGLITERRVH RPYAMMGGEP GQCGANYWVQ KLEDGSERWV
     NIGSRGQVDM KEGDRCVIHT PGGGGWGVPE GLGEDDDEFD GHFEVVNNVN GTNGETKTVY
     PRAAGSFHTF AAAQEASS
//