ID A0A1Y2ZUH4_9GAMM Unreviewed; 808 AA.
AC A0A1Y2ZUH4;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:OTE95504.1};
GN ORFNames=BCS42_01025 {ECO:0000313|EMBL:OTE95504.1};
OS Crenothrix sp. D3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Crenotrichaceae; Crenothrix.
OX NCBI_TaxID=1880899 {ECO:0000313|EMBL:OTE95504.1, ECO:0000313|Proteomes:UP000198219};
RN [1] {ECO:0000313|EMBL:OTE95504.1, ECO:0000313|Proteomes:UP000198219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D3 {ECO:0000313|EMBL:OTE95504.1};
RA Oswald K., Graf J.S., Littman S., Tienken D., Brand A., Wehrli B.,
RA Albertsen M., Daims H., Wagner M., Kuypers M.M., Schubert C.J., Milucka J.;
RT "Crenothrix are major methane consumers in stratified lakes.";
RL ISME J. 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTE95504.1}.
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DR EMBL; MBQZ01000073; OTE95504.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2ZUH4; -.
DR STRING; 1880899.BCS42_01025; -.
DR Proteomes; UP000198219; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033417; CHASE8.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF17152; CHASE8; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 183..236
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 241..311
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 315..366
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 398..531
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 542..797
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 808 AA; 90981 MW; 0703604056065692 CRC64;
MIKRIANLSI KQKLLLIVVF PSVLSLLVVG VFLLLLELSE FQKNKQDDLS AIATIIANRS
TAALLYDDEK IAQENLAVVN TLPEVQAACL YNANGAVFAE LLKPNHGTWH CPATIDGQIT
QFIDTHLCVI EPVIMDLKQQ GTVFIHADFS TAYWRKLQFV GVLFLVLLGV TLLTFLLSAP
LLRLIAEPIR QLVSAVKAIS DSRDYSLRAT KVNDDELGVL VDAFNGLIET VEQQNLALLQ
AKNRYLMLYD DNPTIMFSIN ALGNILSVNR TCANQLGLSS EDLKKHSLFD FIYTSDITII
SAFLEHCLLN QTQIHKEEFR QISGQGQIIW LRVTAKVLDL ENNVNSLLLV CEDITEARNL
NEKIIYQASH DALTGLANRV EFDLYINEAI KLIHVDNSEH ILCYLDLDQF KIINDTCGHL
AGDELLRQLG DVLKKNMRKQ DFIARLGGDE FGVLMYDCSL PEAILLCESL RDIIREFRFF
WEGKSFSIGV SIGLSVINKS SRNAVNLFKE ADSACYAAKD KGRNRIHVYS PDDEELALRH
GEMQWVEKIR HGIENNCFCL YGQPIVSIDK QDEGLHFETL IRYRDESGRI IPPSEFLPAA
ERYDLAPDLD RWVIGSMFEF IATTPRFMDN LAVCSINLSG LSFCDETMLD FIYKQFDLWK
IPEHKICFEI TETAAIANLS STIKFIAALR GRGCLFSLDD FGSGLSSFGY LKNLPVDYLK
IDGLFVKDIL NDKVDLAMVK SINEVGHVMG KKTIAEFVEN EAIFNLLNVL GVDYAQGYGI
SKPVLLTELK LIKPFMTSKN GQKIHHTH
//
