ID A0A1Y2ZY60_9GAMM Unreviewed; 409 AA.
AC A0A1Y2ZY60;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Beta-ketoacyl-ACP synthase II {ECO:0000313|EMBL:OTE96852.1};
GN ORFNames=BCS42_13475 {ECO:0000313|EMBL:OTE96852.1};
OS Crenothrix sp. D3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Crenotrichaceae; Crenothrix.
OX NCBI_TaxID=1880899 {ECO:0000313|EMBL:OTE96852.1, ECO:0000313|Proteomes:UP000198219};
RN [1] {ECO:0000313|EMBL:OTE96852.1, ECO:0000313|Proteomes:UP000198219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D3 {ECO:0000313|EMBL:OTE96852.1};
RA Oswald K., Graf J.S., Littman S., Tienken D., Brand A., Wehrli B.,
RA Albertsen M., Daims H., Wagner M., Kuypers M.M., Schubert C.J., Milucka J.;
RT "Crenothrix are major methane consumers in stratified lakes.";
RL ISME J. 0:0-0(2017).
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTE96852.1}.
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DR EMBL; MBQZ01000029; OTE96852.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2ZY60; -.
DR STRING; 1880899.BCS42_13475; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000198219; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF325; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE II FABF; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 2..406
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 409 AA; 43528 MW; C1E66D1F64C85242 CRC64;
MLKRVVVTGM AGISPIGNDW QQVAARLKSQ ATGIQTMPDW DKYIGLNTRL AAPADFTRPA
HYSRKQTRSM GRVALMATYA TELALIDAGL LNNPCLNSGL MGIAYGSSAG SLDALAEFGN
MLLNHTVNGL NATSYIRMMA HTTAVNIGLF FGINGRIYTT SSACTSSSQG IGYAYEAIKH
GYQTLMVAGG AEELSASEAA VFDTLFATSL RNATPDKSPK PFDRDRDGLV IGEGAGTLIL
EERDHALARG VPIYAELVGF GTNSDGLHVT QPDSHSMQTA MRLALQNAQL DASAIGYISA
HGTATTHGDV AESHATAAVF GTHTPISSLK SFTGHTLGAC GALEAWTAIN MMNEGWFHAT
ANLDNIDSAC APLDYIKGEF RHIDCDYIMS NNFAFGGINT SLVFKRIIQ
//
