ID A0A1Y3A579_9GAMM Unreviewed; 1014 AA.
AC A0A1Y3A579;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BCS42_07615 {ECO:0000313|EMBL:OTE98249.1};
OS Crenothrix sp. D3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Crenotrichaceae; Crenothrix.
OX NCBI_TaxID=1880899 {ECO:0000313|EMBL:OTE98249.1, ECO:0000313|Proteomes:UP000198219};
RN [1] {ECO:0000313|EMBL:OTE98249.1, ECO:0000313|Proteomes:UP000198219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D3 {ECO:0000313|EMBL:OTE98249.1};
RA Oswald K., Graf J.S., Littman S., Tienken D., Brand A., Wehrli B.,
RA Albertsen M., Daims H., Wagner M., Kuypers M.M., Schubert C.J., Milucka J.;
RT "Crenothrix are major methane consumers in stratified lakes.";
RL ISME J. 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTE98249.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MBQZ01000006; OTE98249.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3A579; -.
DR STRING; 1880899.BCS42_07615; -.
DR Proteomes; UP000198219; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR007891; CHASE3.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF3; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR Pfam; PF05227; CHASE3; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 437..509
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 513..566
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 717..763
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 875..1009
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 1014 AA; 114400 MW; 6D95E88BCFCB5D54 CRC64;
MNINIVSYKI PLLAALLAII GGVVVLLGWT LDNNSLKGIL PFWLPMKANA AVCFVLLGSA
IILSDYLPLA LNANTTRICL YVGQACAILA GSISLLTLSE YAFNVNLGID ELLFRDPVDN
AMIAANPMTL QLETTFSGRI KLEAATCFLL LAIASIHSDK NSWRIISASF GVIILALSLA
SLSSILTPSL GQFGWFGYGV MRMNAAVLFA LLGAAEVVIS WRRNVLSWSL SKSITLVFIM
GLFLLILIGF NSSRAQFWLQ STHNDIVFHE NRETELDSLL VSVSKAQTNT RGYVITRNEQ
FLTAFLSAKT DSFIKLNALK QIENSHFMEI DAQVNALFQW YQQVIDSRKI SVPDTNDMIL
HGTDLLDRLT QLLLQLKNED EQHLIELKQS SERVTRFFYR IISIGTLLSV IVFLGVIFRY
NFTESHRKQA EITLRDSERQ LQLVLEGGRL GFWDWNILTN EVQRNVRWAE MLGYSYEEIQ
HTTQQWADFV HPDDREKAWQ SIYDVLEGKK SYHELEYRML HKDGSICWIL DHANIVQHDE
NGKPSRMSGT HSDITERKKI EKTHTFLSQI VHQYTDENFF ITLARYLAQC LDMSFVCIDY
LKSDYLTAKT LAVYHDGLFE DNVEYALKDT PCGNVVGNDI CCFPAHVCQL FPKDEVLKTL
NAESYIGITL WSGTGLPIGL IALIDNKPLA NPELAKSILK IIAGRAAGEL ERLQADIELR
IAATVFESQE SMLIADANSV IIKVNHAFTK MTGYSEAEVL GKNPRLFNSG RHDKAFYTAL
WQSLKDTGTW QGEIWNKRKN GEIYPEWMTI TVVKANKNQQ ITHYVKTATD ITLRKAAEEE
IKQLAFYDPL TGLPNRRKLL DRLRYAITIN HRTNTKFVVF MMDLDKFKAV NDSLGHAAGD
ELLKQVAHRM TGCLRDSDMV ARLGGDEFVL VLENLKIPHD AEIVALKLIT DLTMPFHLSK
NHCVQISATI GISIYPQHGS TPEILMDRAD TALYQAKDDG RGCFAYFADY PSHA
//
