ID   A0A1Y3AUD0_EURMA        Unreviewed;       330 AA.
AC   A0A1Y3AUD0;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=3'5'-cyclic nucleotide phosphodiesterase-like protein {ECO:0000313|EMBL:OTF71066.1};
DE   Flags: Fragment;
GN   ORFNames=BLA29_006384 {ECO:0000313|EMBL:OTF71066.1};
OS   Euroglyphus maynei (Mayne's house dust mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Analgoidea;
OC   Pyroglyphidae; Pyroglyphinae; Euroglyphus.
OX   NCBI_TaxID=6958 {ECO:0000313|EMBL:OTF71066.1, ECO:0000313|Proteomes:UP000194236};
RN   [1] {ECO:0000313|EMBL:OTF71066.1, ECO:0000313|Proteomes:UP000194236}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Arlian Lab {ECO:0000313|EMBL:OTF71066.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OTF71066.1};
RA   Arlian L.G., Morgan M.S., Rider S.D.;
RT   "Genome Survey of Euroglyphus maynei.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OTF71066.1}.
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DR   EMBL; MUJZ01062710; OTF71066.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y3AUD0; -.
DR   OrthoDB; 240889at2759; -.
DR   Proteomes; UP000194236; Unassembled WGS sequence.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.1300.10; 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain; 1.
DR   InterPro; IPR023088; PDEase.
DR   InterPro; IPR002073; PDEase_catalytic_dom.
DR   InterPro; IPR036971; PDEase_catalytic_dom_sf.
DR   PANTHER; PTHR11347:SF198; CAMP-SPECIFIC 3',5'-CAMP PHOSPHODIESTERASE 4; 1.
DR   PANTHER; PTHR11347; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; 1.
DR   Pfam; PF00233; PDEase_I; 1.
DR   PRINTS; PR00387; PDIESTERASE1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS51845; PDEASE_I_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|PIRSR:PIRSR623088-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000194236}.
FT   DOMAIN          1..177
FT                   /note="PDEase"
FT                   /evidence="ECO:0000259|PROSITE:PS51845"
FT   BINDING         81
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR623088-3"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:OTF71066.1"
FT   NON_TER         330
FT                   /evidence="ECO:0000313|EMBL:OTF71066.1"
SQ   SEQUENCE   330 AA;  38545 MW;  9C2D3302BA9DDC7B CRC64;
     SHHWRFALSC FYESHIFDHF DEKQWKEIKF LLKNLILATD ISRQSEFIHQ FKNYIKLGNK
     FSMKKKEHKY FILQIALKCA DLCNPCRPWK ISQRWSEQIC NEFYRQGDFE KLLGLPITPM
     CDRNSTTIPK IQTDFLKNIV RPLFELWNVF LASKLTRQLI NNLNFNEYMW KTMDNMNKSR
     IKRSHSLISL SDKILEKLEI ESNIRYKSYN ELSPLNLSSI ELYENNTIMA EFKPDGNNSK
     SAEKLPKPKC INGCGTPASS KEIITTMASE EKAKLDEDVD FDDEDDDFIS EFNCGAILST
     PALILPNFCY EKPQSGFYRR GSAPGCIDMS
//