ID   A0A1Y3B1C7_EURMA        Unreviewed;       222 AA.
AC   A0A1Y3B1C7;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   28-JUN-2023, entry version 13.
DE   RecName: Full=HMA domain-containing protein {ECO:0000259|PROSITE:PS50846};
DE   Flags: Fragment;
GN   ORFNames=BLA29_008296 {ECO:0000313|EMBL:OTF74601.1};
OS   Euroglyphus maynei (Mayne's house dust mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Analgoidea;
OC   Pyroglyphidae; Pyroglyphinae; Euroglyphus.
OX   NCBI_TaxID=6958 {ECO:0000313|EMBL:OTF74601.1, ECO:0000313|Proteomes:UP000194236};
RN   [1] {ECO:0000313|EMBL:OTF74601.1, ECO:0000313|Proteomes:UP000194236}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Arlian Lab {ECO:0000313|EMBL:OTF74601.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OTF74601.1};
RA   Arlian L.G., Morgan M.S., Rider S.D.;
RT   "Genome Survey of Euroglyphus maynei.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OTF74601.1}.
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DR   EMBL; MUJZ01046252; OTF74601.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y3B1C7; -.
DR   OrthoDB; 5480493at2759; -.
DR   Proteomes; UP000194236; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006825; P:copper ion transport; IEA:UniProtKB-KW.
DR   CDD; cd00371; HMA; 2.
DR   Gene3D; 3.30.70.100; -; 2.
DR   InterPro; IPR017969; Heavy-metal-associated_CS.
DR   InterPro; IPR006121; HMA_dom.
DR   InterPro; IPR036163; HMA_dom_sf.
DR   PANTHER; PTHR46594; P-TYPE CATION-TRANSPORTING ATPASE; 1.
DR   PANTHER; PTHR46594:SF4; P-TYPE CATION-TRANSPORTING ATPASE; 1.
DR   Pfam; PF00403; HMA; 2.
DR   PRINTS; PR00942; CUATPASEI.
DR   SUPFAM; SSF55008; HMA, heavy metal-associated domain; 2.
DR   PROSITE; PS01047; HMA_1; 1.
DR   PROSITE; PS50846; HMA_2; 2.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00022796};
KW   Copper transport {ECO:0000256|ARBA:ARBA00022796};
KW   Ion transport {ECO:0000256|ARBA:ARBA00022796};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000194236};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022796}.
FT   TRANSMEM        183..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          14..80
FT                   /note="HMA"
FT                   /evidence="ECO:0000259|PROSITE:PS50846"
FT   DOMAIN          92..158
FT                   /note="HMA"
FT                   /evidence="ECO:0000259|PROSITE:PS50846"
FT   NON_TER         222
FT                   /evidence="ECO:0000313|EMBL:OTF74601.1"
SQ   SEQUENCE   222 AA;  25031 MW;  47A397B1C84CE74A CRC64;
     MNNSAISSQP QQQRKCFVSI QGMSCSSCVD KIENKLKKTA GVISCQIGLI TARAEIDFDQ
     SIITSEKIID ILDDMGYDVS LISVIDSTNQ QTELRLDVMG IQSENDVKTI QKSVKELIGV
     SMVAINRDTG RTAIVYYPNV IGPRKLADQI VKLGFTVHTI NSFDPEKFTE TLRKEVAKWR
     QSFFISLIFG IPTIIAMIYF MYILSWFEGG NEDHFIVHQR CC
//